{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T20:31:49Z","timestamp":1790713909068,"version":"4.1.0"},"reference-count":37,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T00:00:00Z","timestamp":1787875200000},"content-version":"vor","delay-in-days":239,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transboundary and Emerging Diseases"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>\n                    Companion animals are increasingly recognised within One Health antimicrobial\u2010resistance (AMR) surveillance, yet the global genomic structure of dog\u2010 and cat\u2010associated\n                    <jats:italic>Klebsiella pneumoniae<\/jats:italic>\n                    remains poorly defined. We assembled a global dataset of 712 domestic dog (\n                    <jats:italic>Canis lupus familiaris<\/jats:italic>\n                    )\u2013 and cat (\n                    <jats:italic>Felis catus<\/jats:italic>\n                    )\u2013derived\n                    <jats:italic>K. pneumoniae<\/jats:italic>\n                    genomes to define lineage diversity, AMR burden, host\u2010associated patterns, and overlap with human\u2010associated populations. Companion\u2010animal isolates comprised 263 sequence types (STs), but recurrent high\u2010risk lineages, including ST307, ST11, ST15, and ST147, were prominent. Among 706 isolates from 25 countries, extended\u2010spectrum \u03b2\u2010lactamase (ESBL) and carbapenemase genes were widely distributed, detected in 303 (42.9%) and 98 (13.9%) isolates, respectively. Cat\u2010derived isolates showed higher multidrug\u2010resistance (MDR) prevalence than dog\u2010derived isolates; 80.0% versus 56.3%, partly reflecting enrichment of epidemic clones, especially ST147. MDR was not confined to infection\u2010associated samples, indicating that colonisation may represent an important reservoir state. Comparison with 38,106 human\u2010associated\n                    <jats:italic>K. pneumoniae<\/jats:italic>\n                    isolates revealed extensive ST overlap, with 71.1% of companion\u2010animal STs and 87.2% of companion\u2010animal isolates belonging to STs also detected in humans. Focused recombination\u2010filtered phylogenomics of ST147 identified a closely related MDR cluster containing cat\u2010, dog\u2010 and human\u2010associated genomes, consistent with recent common ancestry and cross\u2010host cocirculation. Together, these findings reveal domestic dogs and cats harbour globally distributed\n                    <jats:italic>K. pneumoniae<\/jats:italic>\n                    lineages and high\u2010risk AMR clones also represented in human\u2010associated populations.\n                  <\/jats:p>","DOI":"10.1155\/tbed\/5383720","type":"journal-article","created":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T09:02:10Z","timestamp":1787907730000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Companion Animals Harbour Globally Circulating Human\u2010Associated\n                    <i>Klebsiella pneumoniae<\/i>\n                    Lineages and High\u2010Risk Antimicrobial Resistance Clones"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7814-2880","authenticated-orcid":false,"given":"Stephen Mark Edward","family":"Fordham","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7804-3217","authenticated-orcid":false,"given":"Elizabeth","family":"Sheridan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5661-2490","authenticated-orcid":false,"given":"Francis","family":"Drobniewski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,28]]},"reference":[{"key":"e_1_2_11_1_2","unstructured":"World Health Organization (WHO) Global Antibiotic Resistance Surveillance Report 2025 2025 https:\/\/www.who.int\/publications\/i\/item\/9789240116337."},{"key":"e_1_2_11_2_2","unstructured":"UK Pet Food UK Pet Population 2026 2026 https:\/\/www.ukpetfood.org\/industry-hub\/data-statistics-\/uk-pet-population-.html."},{"key":"e_1_2_11_3_2","unstructured":"FEDIAF Facts & Figures 2025: Based on Aggregated Data From 2023 2025 European Pet Food Industry Federation https:\/\/europeanpetfood.org\/wp-content\/uploads\/2025\/06\/FEDIAF-Facts-Figures-2025.pdf."},{"key":"e_1_2_11_4_2","unstructured":"American Veterinary Medical Association U.S. Pet Ownership Statistics 2025 https:\/\/www.avma.org\/resources-tools\/reports-statistics\/us-pet-ownership-statistics."},{"key":"e_1_2_11_5_2","volume-title":"Strengthening Antimicrobial Resistance Surveillance in Pets and Horses","author":"Dew\u00e9 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