{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T14:49:00Z","timestamp":1785163740568,"version":"3.55.0"},"reference-count":36,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T00:00:00Z","timestamp":1775865600000},"content-version":"vor","delay-in-days":100,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Breast Journal"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>Omission of sentinel node biopsy is increasingly offered to selected older women with cN0 low\u2010risk breast cancer (BC). We hypothesized that some younger women might exhibit a low enough incidence of lymph node metastases to possibly justify excluding axillary surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We statistically analyzed, using parametric and nonparametric tests as appropriate, multiple demographic and clinicopathologic variables in cT1\u20102\u2009N0 M0 BC patients of all ages undergoing axillary LN excisional surgery from a long\u2010term, prospectively maintained database.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Patients with (816) and without (3617) LN metastases were compared. Although older patients were significantly (\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.0001) less likely to have LN metastases compared to younger patients, 3\/61 (4.92%) of those &lt;\u200950\u2009years old with grade 1 tumors \u2264\u20091\u2009cm in size (T1a and b) and no lymphovascular invasion had LN metastases compared to 30\/504 (5.95%)\u2009\u2265\u200950. Patients aged 50 or older with Grade 2\/3, &lt;\u20091\u2009cm, LVI\u2010negative tumors had only 53\/774 (6.85%) LN positive, compared to 19\/131 (14.5%) in women &lt;\u200950 with the same pathology.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Women with grade 1, \u2264\u20091\u2009cm invasive BCs, and no LVI had &lt;\u20096% incidence of LN metastases regardless of age. Instead of excluding younger women from axillary node surgery de\u2010escalation strategies, this study suggests that any woman with a tumor size \u2264\u20091\u2009cm, Grade 1, and no LVI could be evaluated in prospective studies whose objective is to safely avoid axillary LN surgery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/tbj\/6196988","type":"journal-article","created":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T15:51:09Z","timestamp":1775922669000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Selected Pathological Criteria That Predict Low Rates of Axillary Lymph Node Metastases Regardless of Patient Age: A Single Institution Study"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5254-9789","authenticated-orcid":false,"given":"S. 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