{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T11:41:53Z","timestamp":1776512513481,"version":"3.51.2"},"reference-count":38,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T00:00:00Z","timestamp":1776470400000},"content-version":"vor","delay-in-days":107,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82241219"],"award-info":[{"award-number":["82241219"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81921004"],"award-info":[{"award-number":["81921004"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Breast Journal"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To investigate cardiovascular disease (CVD) mortality among patients with different breast cancer (BC) subtypes to assess its implications for long\u2010term survival.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>In total, 423,758 BC patients were included in this study utilizing data from the Surveillance, Epidemiology, and End Results 17 Registries Database (2010\u20132020). Competing risk curves were utilized to assess whether the cumulative CVD mortality surpassed the cumulative BC mortality. Multivariate competing risk models were used to explore potential factors associated with CVD mortality. Standardized mortality ratios (SMRs) were calculated to investigate CVD mortality in comparison to the general population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In total, 5863 BC patients died from CVD during follow\u2010up time, accounting for 10.0% of all deaths (56,856). The number of deaths and the percentage of all deaths among patients died from CVD for luminal A, luminal B, HER\u20102 enriched, and triple\u2010negative subtype were 4160 (12.2%), 615 (9.7%), 291 (7.7%), and 797 (6.2%), respectively. After 9\u2009years, BC mortality remained over 10% higher than CVD mortality for luminal A and B subtypes, but the difference was under 10% for HER\u20102\u2010enriched and triple\u2010negative subtypes. HER\u20102\u2010enriched and triple\u2010negative BC patients aged 55\u201384 had higher CVD mortality compared to the general population. Triple\u2010negative BC was independently associated with increased CVD mortality compared with luminal A (HR 1.103 [95% CI: 1.016\u20131.199]).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Patients with the triple\u2010negative subtype have a high risk of CVD mortality. This underscores the need for enhanced surveillance and targeted cardiovascular interventions for these patients to improve their long\u2010term health outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1155\/tbj\/8076118","type":"journal-article","created":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T10:49:16Z","timestamp":1776509356000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Cohort Study on Cardiovascular Disease Mortality in Breast Cancer Patients With Different Subtypes"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5686-927X","authenticated-orcid":false,"given":"Zhipeng","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0569-6188","authenticated-orcid":false,"given":"Lihong","family":"Deng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4803-2549","authenticated-orcid":false,"given":"Peng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3592-9480","authenticated-orcid":false,"given":"Yacong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-2212-4539","authenticated-orcid":false,"given":"Zhongyang","family":"Shen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,4,18]]},"reference":[{"key":"e_1_2_15_1_2","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21763"},{"key":"e_1_2_15_2_2","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21731"},{"key":"e_1_2_15_3_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.21.01736"},{"key":"e_1_2_15_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehz766"},{"key":"e_1_2_15_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2016.3841"},{"key":"e_1_2_15_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2022.04.042"},{"key":"e_1_2_15_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tjog.2015.12.005"},{"key":"e_1_2_15_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2015.11.040"},{"key":"e_1_2_15_9_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000556"},{"key":"e_1_2_15_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.2012"},{"key":"e_1_2_15_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/dju055"},{"key":"e_1_2_15_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.annonc.2023.08.017"},{"key":"e_1_2_15_13_2","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-18-0502"},{"key":"e_1_2_15_14_2","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-16-2574"},{"key":"e_1_2_15_15_2","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djy218"},{"key":"e_1_2_15_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.34224"},{"key":"e_1_2_15_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djs317"},{"key":"e_1_2_15_18_2","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mds127"},{"key":"e_1_2_15_19_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehy167"},{"key":"e_1_2_15_20_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-15639-5"},{"key":"e_1_2_15_21_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2016.67.5140"},{"key":"e_1_2_15_22_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19951201)76:11<2343::aid-cncr2820761124>3.0.co;2-#;"},{"key":"e_1_2_15_23_2","volume-title":"Incidence-SEER Research plus Data, 18 Registries, Nov 2020 Sub (2000-2018)-Linked to County Attributes-Total U.S., 1969-2019 Counties","author":"Surveillance, Epidemiology, and End Results (SEER) Program","year":"2021"},{"key":"e_1_2_15_24_2","unstructured":"Centers for Disease Control and PreventionandNational Center for Health Statistics National Vital Statistics System Mortality 1999\u20132020 on CDC WONDER Online Database Released in 2021. 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