{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T14:43:20Z","timestamp":1786632200047,"version":"build-2736575974"},"reference-count":70,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T00:00:00Z","timestamp":1786579200000},"content-version":"vor","delay-in-days":224,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Scientific World Journal"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>\n                    Stunting remains a pressing public health problem in low\u2010 and middle\u2010income countries. The specific biochemical roles of growth\u2010 and immune\u2010related biomarkers with stunting are less understood. This study is aimed at investigating the contribution of insulin\u2010like growth factor 1 (IGF\u20101) and interleukin\u201010 (IL\u201010) to stunting among Indonesian children. A case\u2010control design was employed involving 80 children aged 24\u201360 months in Manggarai, Indonesia (40 stunted and 40 nonstunted), matched by age, sex, and residence. Data were collected through anthropometric measurements, household surveys, structured interviews, and biochemical analysis of serum IGF\u20101 and IL\u201010 using ELISA. Findings revealed that stunted children had significantly lower IGF\u20101 levels (11.963 \u00b1 8.658 vs. 18.000 \u00b1 15.238,\n                    <jats:italic>p<\/jats:italic>\n                    &lt; 0.05) and higher IL\u201010 levels (317.841 \u00b1 214.934 vs. 543.605 \u00b1 416.837,\n                    <jats:italic>p<\/jats:italic>\n                    &lt; 0.05) compared with controls. The study concludes that effective stunting prevention requires integrated interventions addressing both nutritional adequacy and infection control in early childhood.\n                  <\/jats:p>","DOI":"10.1155\/tswj\/1029295","type":"journal-article","created":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T13:52:46Z","timestamp":1786629166000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Role of IGF\u20101 and IL\u201010 in Childhood Stunting: Evidence From Indonesia"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3822-4301","authenticated-orcid":false,"given":"Putriatri Krimasusini","family":"Senudin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7573-8793","authenticated-orcid":false,"family":"Irwanto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4253-8760","authenticated-orcid":false,"given":"Nur Aisiyah","family":"Widjaja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7907-5598","authenticated-orcid":false,"family":"Sulistiawati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,13]]},"reference":[{"key":"e_1_2_13_1_2","doi-asserted-by":"publisher","DOI":"10.1051\/e3sconf\/20187409007"},{"key":"e_1_2_13_2_2","doi-asserted-by":"publisher","DOI":"10.18697\/ajfand.136.24575"},{"key":"e_1_2_13_3_2","first-page":"315","article-title":"Stunting Trends and Associated Factors Among Indonesian Children Aged 0-23 Months: Evidence From Indonesian Family Life Surveys (IFLS) 2000, 2007 and 2014","volume":"24","author":"Hanifah L.","year":"2018","journal-title":"Malaysian Journal of Nutrition"},{"key":"e_1_2_13_4_2","doi-asserted-by":"publisher","DOI":"10.1177\/10105395251337970"},{"key":"e_1_2_13_5_2","doi-asserted-by":"publisher","DOI":"10.61251\/sajtmph.v54i2.1049"},{"key":"e_1_2_13_6_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2024-089531"},{"key":"e_1_2_13_7_2","doi-asserted-by":"publisher","DOI":"10.28919\/cmbn\/8929"},{"key":"e_1_2_13_8_2","doi-asserted-by":"publisher","DOI":"10.56338\/mppki.v4i3.1616"},{"key":"e_1_2_13_9_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-024-18824-z"},{"key":"e_1_2_13_10_2","doi-asserted-by":"publisher","DOI":"10.20473\/mgi.v19i1.17-27"},{"key":"e_1_2_13_11_2","doi-asserted-by":"publisher","DOI":"10.20473\/mgi.v19i3.282-290"},{"key":"e_1_2_13_12_2","doi-asserted-by":"publisher","DOI":"10.1080\/03014460.2021.1998622"},{"key":"e_1_2_13_13_2","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1017\/CBO9780511781193.029","volume-title":"Human Evolutionary Biology","author":"Ulijaszek S. 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