{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T11:06:19Z","timestamp":1789211179026,"version":"build-2803163510"},"reference-count":39,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T00:00:00Z","timestamp":1789171200000},"content-version":"vor","delay-in-days":254,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100017170","name":"Thailand Science Research and Innovation","doi-asserted-by":"publisher","award":["FF68\/KKC\/043"],"award-info":[{"award-number":["FF68\/KKC\/043"]}],"id":[{"id":"10.13039\/501100017170","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Scientific World Journal"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>\n                    This study investigated the effects of solvent composition and sonication time on the ultrasound\u2010assisted extraction of phenolic\u2010rich peppermint extracts using ethanol\u2013water mixtures. Ethanol concentrations of 0%, 50%, 75%, and 95% were applied for extraction periods of 15 and 30\u2009min, and the resulting extracts were evaluated for total phenolic content (TPC), total flavonoid content (TFC), and antioxidant activities using DPPH and ABTS assays. Two\u2010way ANOVA revealed that ethanol concentration, sonication time, and their interaction significantly affected all measured parameters (\n                    <jats:italic>p<\/jats:italic>\n                    &lt; 0.01). The optimal extraction condition was 50% ethanol for 15\u2009min, which produced the highest TPC (141.64 \u00b1 3.34\u2009mg GAE\/g extract) and TFC (256.20 \u00b1 2.43\u2009mg RE\/g extract), together with the strongest antioxidant activities, as indicated by the lowest IC\n                    <jats:sub>50<\/jats:sub>\n                    values for DPPH (0.123 \u00b1 0.001\u2009mg\/mL) and ABTS (0.023 \u00b1 0.001\u2009mg\/mL) radical scavenging activity. Correlation analysis demonstrated strong negative relationships between phytochemical contents and antioxidant IC\n                    <jats:sub>50<\/jats:sub>\n                    values, indicating that increased phenolic and flavonoid contents were associated with enhanced antioxidant activity. Prolonged sonication generally reduced extraction efficiency under certain solvent conditions, particularly at intermediate ethanol concentrations, suggesting possible degradation of sensitive phytochemicals during extended cavitation. These findings demonstrate the importance of balancing solvent polarity and extraction duration to maximize phytochemical recovery and antioxidant activity under green extraction conditions.\n                  <\/jats:p>","DOI":"10.1155\/tswj\/4620252","type":"journal-article","created":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T10:22:37Z","timestamp":1789208557000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Green Extraction Approach for Phenolic\u2010Rich Peppermint Extracts Using Ultrasound: Impact of Solvent and Time Variables"],"prefix":"10.1155","volume":"2026","author":[{"given":"Kantapon","family":"Premprayoon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-0315-9895","authenticated-orcid":false,"given":"Tossapol","family":"Jangnoi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Likit","family":"Temprom","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7979-1471","authenticated-orcid":false,"given":"Khakhanang","family":"Ratananikom","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,12]]},"reference":[{"key":"e_1_2_12_1_2","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/162750"},{"key":"e_1_2_12_2_2","doi-asserted-by":"publisher","DOI":"10.30574\/gscbps.2023.24.3.0372"},{"key":"e_1_2_12_3_2","doi-asserted-by":"publisher","DOI":"10.3390\/antiox10081264"},{"key":"e_1_2_12_4_2","doi-asserted-by":"crossref","first-page":"2500","DOI":"10.1002\/fsn3.3308","article-title":"Phytobioactive Compounds as Therapeutic Agents for Human Diseases: A Review","volume":"11","author":"Riaz M.","year":"2023","journal-title":"Food Science & Nutrition"},{"key":"e_1_2_12_5_2","doi-asserted-by":"publisher","DOI":"10.3390\/molecules29163861"},{"key":"e_1_2_12_6_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.3c01656"},{"key":"e_1_2_12_7_2","article-title":"Influence of Extraction Technologies on the Therapeutic Properties of Pleurotus spp. (Oyster Mushrooms)-A Critical Review. 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