{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T07:24:30Z","timestamp":1789457070323,"version":"build-2803163510"},"reference-count":140,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T00:00:00Z","timestamp":1758672000000},"content-version":"vor","delay-in-days":266,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Scientific World Journal"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>\n                    Bacterial infections, particularly those caused by Gram\u2010positive bacteria like vancomycin\u2010resistant enterococci (VRE) and methicillin\u2010resistant\n                    <jats:italic>Staphylococcus aureus<\/jats:italic>\n                    (MRSA), are a growing concern. This review highlights the potential of the\n                    <jats:italic>Streptomyces<\/jats:italic>\n                    genus in producing novel antibacterial compounds against Gram\u2010positive bacteria. The study was carried out following the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta\u2010Analysis (PRISMA). To gather relevant literature on novel anti\u2010Gram\u2010positive bacteria compounds produced by\n                    <jats:italic>Streptomyces<\/jats:italic>\n                    , a web search was conducted using several databases, including Scopus, PubMed, ScienceDirect, and Google Scholar, covering the period from January 2013 to mid\u20102024. The search terms employed in this study included \u201c\n                    <jats:italic>Streptomyces<\/jats:italic>\n                    ,\u201d \u201cantimicrobial\/antibacterial activity,\u201d \u201ccompounds,\u201d and \u201cGram\u2010positive bacteria.\u201d Consequently, a total of 248\n                    <jats:italic>Streptomyces<\/jats:italic>\n                    \u2010derived compounds were featured across the 96 eligible studies. These compounds include 100 polyketides (58 aromatic polyketides, 30 macrolides, and 12 other polyketides), 72 peptides (67 nonribosomal peptides [52 typical cyclic peptides and 15 lipopeptides] and 5 ribosomal peptides), 23 terpenoids, five polyketides\u2013terpenoids, six alkaloids, 12 phenazines, 11 nucleoside antibiotics, and 19 other compounds belonging to distinct chemical classes. The results emphasize that\n                    <jats:italic>Streptomyces<\/jats:italic>\n                    is an unlimited source of naturally occurring compounds with various structural variations that can occasionally have targeted action against a range of pathogenic Gram\u2010positive bacteria.\n                  <\/jats:p>","DOI":"10.1155\/tswj\/6659874","type":"journal-article","created":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T13:20:17Z","timestamp":1758720017000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["New\n                    <i>Streptomyces<\/i>\n                    \u2010Derived Antibacterial Compounds Targeting Gram\u2010Positive Bacteria: A Systematic Review"],"prefix":"10.1155","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8041-9850","authenticated-orcid":false,"given":"Soumia","family":"Ait Assou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1423-8795","authenticated-orcid":false,"given":"Mohammed","family":"El Hassouni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,9,24]]},"reference":[{"key":"e_1_2_11_1_2","unstructured":"WHO Antimicrobial Resistance 2021 Available at:https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/antimicrobial-resistance. Accessed 06 September 2023."},{"key":"e_1_2_11_2_2","doi-asserted-by":"publisher","DOI":"10.1089\/mdr.2018.0319"},{"key":"e_1_2_11_3_2","doi-asserted-by":"publisher","DOI":"10.4103\/2045-080X.186181"},{"key":"e_1_2_11_4_2","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines8100405"},{"key":"e_1_2_11_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciw828"},{"key":"e_1_2_11_6_2","unstructured":"WHO WHO Updates List of Drug-Resistant Bacteria Most Threatening to Human Health 2024 Available at:https:\/\/www.who.int\/news\/item\/17-05-2024-who-updates-list-of-drug-resistant-bacteria-most-threatening-to-human-health. Accessed 13 November 2024."},{"key":"e_1_2_11_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.glmedi.2024.100081"},{"key":"e_1_2_11_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/ja.2012.27"},{"key":"e_1_2_11_9_2","doi-asserted-by":"publisher","DOI":"10.1039\/b817069j"},{"key":"e_1_2_11_10_2","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics8040157"},{"key":"e_1_2_11_11_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-24921-y"},{"key":"e_1_2_11_12_2","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics13040362"},{"key":"e_1_2_11_13_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2018.02221"},{"key":"e_1_2_11_14_2","doi-asserted-by":"publisher","DOI":"10.3390\/molecules26092754"},{"key":"e_1_2_11_15_2","doi-asserted-by":"publisher","DOI":"10.3390\/md22010051"},{"key":"e_1_2_11_16_2","doi-asserted-by":"publisher","DOI":"10.3390\/molecules27030887"},{"key":"e_1_2_11_17_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71"},{"key":"e_1_2_11_18_2","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms7050124"},{"key":"e_1_2_11_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0076-6879(09)04602-3"},{"key":"e_1_2_11_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.myc.2020.03.001"},{"key":"e_1_2_11_21_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00253-017-8396-0"},{"key":"e_1_2_11_22_2","doi-asserted-by":"publisher","DOI":"10.1039\/c2np20070h"},{"key":"e_1_2_11_23_2","doi-asserted-by":"publisher","DOI":"10.3390\/md12010317"},{"key":"e_1_2_11_24_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.6b00591"},{"key":"e_1_2_11_25_2","doi-asserted-by":"publisher","DOI":"10.1038\/ja.2014.171"},{"key":"e_1_2_11_26_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0033-1340624"},{"key":"e_1_2_11_27_2","doi-asserted-by":"publisher","DOI":"10.3390\/md13084814"},{"key":"e_1_2_11_28_2","doi-asserted-by":"publisher","DOI":"10.1021\/cr020473j"},{"key":"e_1_2_11_29_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41429-019-0236-2"},{"key":"e_1_2_11_30_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jnatprod.9b00198"},{"key":"e_1_2_11_31_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jnatprod.4c00232"},{"key":"e_1_2_11_32_2","doi-asserted-by":"publisher","DOI":"10.1039\/c6sc04265a"},{"key":"e_1_2_11_33_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41429-020-0277-6"},{"key":"e_1_2_11_34_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsps.2019.06.004"},{"key":"e_1_2_11_35_2","doi-asserted-by":"publisher","DOI":"10.1080\/14786419.2019.1577835"},{"key":"e_1_2_11_36_2","doi-asserted-by":"publisher","DOI":"10.3390\/md13031304"},{"key":"e_1_2_11_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tetlet.2013.10.112"},{"key":"e_1_2_11_38_2","doi-asserted-by":"publisher","DOI":"10.3389\/fchem.2020.00586"},{"key":"e_1_2_11_39_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jnatprod.5b00601"},{"key":"e_1_2_11_40_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms232213779"},{"key":"e_1_2_11_41_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41429-020-0290-9"},{"key":"e_1_2_11_42_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41429-018-0103-6"},{"key":"e_1_2_11_43_2","doi-asserted-by":"publisher","DOI":"10.1038\/ja.2014.128"},{"key":"e_1_2_11_44_2","doi-asserted-by":"publisher","DOI":"10.3390\/md14010010"},{"key":"e_1_2_11_45_2","doi-asserted-by":"publisher","DOI":"10.3390\/molecules24183384"},{"key":"e_1_2_11_46_2","doi-asserted-by":"publisher","DOI":"10.1038\/ja.2013.12"},{"key":"e_1_2_11_47_2","doi-asserted-by":"publisher","DOI":"10.3390\/molecules22020251"},{"key":"e_1_2_11_48_2","doi-asserted-by":"publisher","DOI":"10.1038\/ja.2015.143"},{"key":"e_1_2_11_49_2","doi-asserted-by":"publisher","DOI":"10.1038\/ja.2016.122"},{"key":"e_1_2_11_50_2","doi-asserted-by":"publisher","DOI":"10.1038\/aps.2013.155"},{"key":"e_1_2_11_51_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201302749"},{"key":"e_1_2_11_52_2","doi-asserted-by":"publisher","DOI":"10.3390\/md16110406"},{"key":"e_1_2_11_53_2","doi-asserted-by":"publisher","DOI":"10.1080\/14786419.2020.1797730"},{"key":"e_1_2_11_54_2","doi-asserted-by":"publisher","DOI":"10.1002\/cbic.201800266"},{"key":"e_1_2_11_55_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tetlet.2018.11.023"},{"key":"e_1_2_11_56_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jnatprod.6b00200"},{"key":"e_1_2_11_57_2","doi-asserted-by":"publisher","DOI":"10.3390\/md11103891"},{"key":"e_1_2_11_58_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00253-012-4681-0"},{"key":"e_1_2_11_59_2","doi-asserted-by":"publisher","DOI":"10.1038\/ja.2015.60"},{"key":"e_1_2_11_60_2","doi-asserted-by":"publisher","DOI":"10.1002\/cbdv.201900560"},{"key":"e_1_2_11_61_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12934-015-0359-5"},{"key":"e_1_2_11_62_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jnatprod.8b00448"},{"key":"e_1_2_11_63_2","doi-asserted-by":"publisher","DOI":"10.1080\/14786419.2021.1881517"},{"key":"e_1_2_11_64_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0043-111897"},{"key":"e_1_2_11_65_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.phytochem.2017.09.010"},{"key":"e_1_2_11_66_2","doi-asserted-by":"publisher","DOI":"10.1021\/np500757w"},{"key":"e_1_2_11_67_2","doi-asserted-by":"publisher","DOI":"10.1021\/np4003417"},{"key":"e_1_2_11_68_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41429-020-0298-1"},{"key":"e_1_2_11_69_2","doi-asserted-by":"publisher","DOI":"10.3390\/md22060259"},{"key":"e_1_2_11_70_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tet.2018.08.023"},{"key":"e_1_2_11_71_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jnatprod.0c00151"},{"key":"e_1_2_11_72_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.2c02493"},{"key":"e_1_2_11_73_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24021114"},{"key":"e_1_2_11_74_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-03769-8"},{"key":"e_1_2_11_75_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-06736-0"},{"key":"e_1_2_11_76_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.7b00228"},{"key":"e_1_2_11_77_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10600-013-0775-x"},{"key":"e_1_2_11_78_2","doi-asserted-by":"publisher","DOI":"10.1038\/ja.2014.1"},{"key":"e_1_2_11_79_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jnatprod.9b01095"},{"key":"e_1_2_11_80_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tet.2014.02.007"},{"key":"e_1_2_11_81_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202012902"},{"key":"e_1_2_11_82_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41429-019-0272-y"},{"key":"e_1_2_11_83_2","doi-asserted-by":"publisher","DOI":"10.1002\/ejoc.201600297"},{"key":"e_1_2_11_84_2","doi-asserted-by":"publisher","DOI":"10.3390\/md13116947"},{"key":"e_1_2_11_85_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jnatprod.1c00547"},{"key":"e_1_2_11_86_2","doi-asserted-by":"publisher","DOI":"10.1021\/np500399v"},{"key":"e_1_2_11_87_2","doi-asserted-by":"publisher","DOI":"10.1021\/cr60292a002"},{"key":"e_1_2_11_88_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202410286"},{"key":"e_1_2_11_89_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202104528"},{"key":"e_1_2_11_90_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jnatprod.8b00497"},{"key":"e_1_2_11_91_2","doi-asserted-by":"publisher","DOI":"10.1080\/14786419.2014.886210"},{"key":"e_1_2_11_92_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13568-014-0050-y"},{"key":"e_1_2_11_93_2","doi-asserted-by":"publisher","DOI":"10.1080\/14786419.2013.811661"},{"key":"e_1_2_11_94_2","doi-asserted-by":"publisher","DOI":"10.3390\/md22060262"},{"key":"e_1_2_11_95_2","doi-asserted-by":"publisher","DOI":"10.1002\/chem.202403985"},{"key":"e_1_2_11_96_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tetlet.2017.12.056"},{"key":"e_1_2_11_97_2","doi-asserted-by":"publisher","DOI":"10.1021\/acschembio.5b00584"},{"key":"e_1_2_11_98_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2018.11.007"},{"key":"e_1_2_11_99_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202005187"},{"key":"e_1_2_11_100_2","doi-asserted-by":"publisher","DOI":"10.1002\/cbic.202100132"},{"key":"e_1_2_11_101_2","doi-asserted-by":"publisher","DOI":"10.3390\/md11062113"},{"key":"e_1_2_11_102_2","doi-asserted-by":"publisher","DOI":"10.3390\/md19110618"},{"key":"e_1_2_11_103_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25063311"},{"key":"e_1_2_11_104_2","doi-asserted-by":"publisher","DOI":"10.3390\/md18010022"},{"key":"e_1_2_11_105_2","doi-asserted-by":"publisher","DOI":"10.1002\/ejoc.201300349"},{"key":"e_1_2_11_106_2","doi-asserted-by":"publisher","DOI":"10.3390\/molecules28020640"},{"key":"e_1_2_11_107_2","doi-asserted-by":"publisher","DOI":"10.3390\/biom10081187"},{"key":"e_1_2_11_108_2","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics11111587"},{"key":"e_1_2_11_109_2","doi-asserted-by":"publisher","DOI":"10.3390\/md21030167"},{"key":"e_1_2_11_110_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41429-020-0307-4"},{"key":"e_1_2_11_111_2","doi-asserted-by":"publisher","DOI":"10.3390\/md15080244"},{"key":"e_1_2_11_112_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1875-5364(19)30055-X"},{"key":"e_1_2_11_113_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41429-020-0282-9"},{"key":"e_1_2_11_114_2","doi-asserted-by":"publisher","DOI":"10.1038\/ja.2014.124"},{"key":"e_1_2_11_115_2","doi-asserted-by":"crossref","unstructured":"WangX. AbbasM. ZhangY. ElshahawiS. I. PonomarevaL. V. CuiZ. Van LanenS. G. SajidI. Randal VossS. ShaabanK. A. andThorsonJ. S. Baraphenazines A\u2013G Divergent Fused Phenazine-Based Metabolites From a HimalayanStreptomyces 2019 82 no. 6 1686\u20131693 https:\/\/doi.org\/10.1021\/acs.jnatprod.9b00289 2-s2.0-85068221109 31117525.","DOI":"10.1021\/acs.jnatprod.9b00289"},{"key":"e_1_2_11_116_2","doi-asserted-by":"publisher","DOI":"10.1128\/aac.00917-23"},{"key":"e_1_2_11_117_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41429-024-00724-4"},{"key":"e_1_2_11_118_2","doi-asserted-by":"publisher","DOI":"10.3390\/md12126102"},{"key":"e_1_2_11_119_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-14549-4"},{"key":"e_1_2_11_120_2","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics9050252"},{"key":"e_1_2_11_121_2","doi-asserted-by":"publisher","DOI":"10.3390\/md20060394"},{"key":"e_1_2_11_122_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jnatprod.2c00438"},{"key":"e_1_2_11_123_2","doi-asserted-by":"publisher","DOI":"10.1038\/ja.2017.26"},{"key":"e_1_2_11_124_2","doi-asserted-by":"publisher","DOI":"10.1038\/ja.2017.50"},{"key":"e_1_2_11_125_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2023.1182449"},{"key":"e_1_2_11_126_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jnatprod.5b00276"},{"key":"e_1_2_11_127_2","doi-asserted-by":"publisher","DOI":"10.1177\/1934578X20920042"},{"key":"e_1_2_11_128_2","doi-asserted-by":"publisher","DOI":"10.1080\/14786419.2013.793688"},{"key":"e_1_2_11_129_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.2011.01250.x"},{"key":"e_1_2_11_130_2","doi-asserted-by":"publisher","DOI":"10.4155\/fmc-2020-0225"},{"key":"e_1_2_11_131_2","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics8010008"},{"key":"e_1_2_11_132_2","volume-title":"Antimicrobial Resistance in the EU\/EEA (EARS-Net) - Annual Epidemiological Report 2019","author":"CDC (European Centre for Disease Prevention and Control)","year":"2020"},{"key":"e_1_2_11_133_2","doi-asserted-by":"publisher","DOI":"10.2174\/0929867324666170918122633"},{"key":"e_1_2_11_134_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M117.791269"},{"key":"e_1_2_11_135_2","doi-asserted-by":"publisher","DOI":"10.7164\/antibiotics.35.645"},{"key":"e_1_2_11_136_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibs.2018.06.011"},{"key":"e_1_2_11_137_2","doi-asserted-by":"publisher","DOI":"10.1038\/ja.2014.36"},{"key":"e_1_2_11_138_2","doi-asserted-by":"publisher","DOI":"10.1039\/d2sc05049h"},{"key":"e_1_2_11_139_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02204-18"},{"key":"e_1_2_11_140_2","doi-asserted-by":"publisher","DOI":"10.3390\/microbiolres13030031"}],"container-title":["The Scientific World Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/tswj\/6659874","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/tswj\/6659874","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/tswj\/6659874","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T10:55:23Z","timestamp":1772967323000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/tswj\/6659874"}},"subtitle":[],"editor":[{"given":"Arun","family":"Suneja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":140,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1155\/tswj\/6659874"],"URL":"https:\/\/doi.org\/10.1155\/tswj\/6659874","archive":["Portico"],"relation":{},"ISSN":["2356-6140","1537-744X"],"issn-type":[{"value":"2356-6140","type":"print"},{"value":"1537-744X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"2025-04-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-30","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"6659874"}}