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These materials were used in different biomedical applications, because of the superior quality of nanoparticles and nano\u2010oxide materials compared with their bulky counterparts in the fields of medicine and healthcare. This gives a push to this line of science toward making a great progress. Despite the positive benefits associated with nanofield usages, nanomaterials have cytotoxic effects which are directly associated with their physiochemical properties. Therefore, proper control of factors governing nanoparticle synthesis can improve biocompatibility and minimize toxicity, which would enable researchers to achieve more suitable outcomes. In our review, we focus on the significant progress in the field of MONPs, covering their synthesis and applications, as well as the methods of preparations and their chemical or physical qualities. In addition to their antibacterial effectiveness, MONPs also exhibit biological effects, like antitumor, anticancer, proregenerative, and drug delivery properties. 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