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A total of 192 Cobb\u2010500 broilers were assigned to four dietary treatments (0%, 1.5%, 3.0%, and 4.5% soaked CSK) in a completely randomized design with four replicates and 12 birds per replicate. The birds were fed isocaloric and isonitrogenous diets for 42\u2009days. Majority of the optimal results were observed at the 1.5% and 3.0% soaked CSK inclusion levels, as evidenced by significant quadratic trends. Breast and thigh meat quality showed quadratic improvements in protein content, fat reduction, drip and cooking loss reduction, redness, and sensory scores (juiciness and tenderness). Key blood parameters (red blood cells, hemoglobin, total protein, immunoglobulins, and globulins) were improved quadratically, while serum triglycerides and cholesterol decreased linearly. Additionally, all soaked CSK inclusion levels quadratically reduced pathogenic E. coli and coliforms without impacting beneficial Lactobacilli and Enterococcus spp. Based on these results, dietary inclusion of soaked CSK meal up to 3.0% is a safe and effective strategy for simultaneously enhancing broiler meat physicochemical quality, improving metabolic and immune status, and promoting a beneficial gut microbiota balance.<\/jats:p>","DOI":"10.1155\/vmi\/2733198","type":"journal-article","created":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T11:10:51Z","timestamp":1786619451000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Dietary Inclusion of Casimiroa (\n                    <i>Casimiroa edulis<\/i>\n                    L) Seed Kernel Meal on Meat Qualities, Blood Profiles, and Cecal Microbiota of Broiler Chicken"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-8243-7276","authenticated-orcid":false,"given":"Mohammedjuhar Musa","family":"Adame","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengistu Urge","family":"Letta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Biazen Abrar","family":"Bedru","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0390-5772","authenticated-orcid":false,"given":"Sileshi Gadissa","family":"Terfa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meseret Girma","family":"Abebe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Misba Alewi","family":"Abdu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,13]]},"reference":[{"key":"e_1_2_13_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.psj.2025.105626"},{"key":"e_1_2_13_2_2","doi-asserted-by":"publisher","DOI":"10.4315\/0362-028X.JFP-17-086"},{"key":"e_1_2_13_3_2","doi-asserted-by":"publisher","DOI":"10.22271\/veterinary.2025.v10.i9c.2549"},{"key":"e_1_2_13_4_2","doi-asserted-by":"publisher","DOI":"10.3390\/antiox10050659"},{"key":"e_1_2_13_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.biteb.2025.102159"},{"key":"e_1_2_13_6_2","doi-asserted-by":"publisher","DOI":"10.3923\/ijp.2015.152.176"},{"key":"e_1_2_13_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10457-019-00424-1"},{"key":"e_1_2_13_8_2","doi-asserted-by":"publisher","DOI":"10.1186\/s42269-020-00396-8"},{"key":"e_1_2_13_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11250-025-04549-7"},{"key":"e_1_2_13_10_2","doi-asserted-by":"publisher","DOI":"10.1186\/s40066-024-00508-x"},{"key":"e_1_2_13_11_2","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms7100374"},{"key":"e_1_2_13_12_2","doi-asserted-by":"publisher","DOI":"10.21273\/HORTSCI12432-17"},{"key":"e_1_2_13_13_2","volume-title":"Characterization and Optimization of Casimiroa (Casimiroa edulis L) Fruit Juice","author":"Zeru T.","year":"2018"},{"key":"e_1_2_13_14_2","first-page":"1574","article-title":"Review on Distribution, Nutritional and Medicinal Values of Casimiroa Edulus Llave-an Underutilized Fruit in Ethiopia","volume":"15","author":"Satheesh N.","year":"2015","journal-title":"American-Eurasian Journal of Agricultural & Environmental Sciences"},{"key":"e_1_2_13_15_2","article-title":"Assessment of the Feeding Potential and Utilization of Erythrina burana and Casimiroa edulis in Eastern Harerghe Zone of Ethiopia","volume":"26","author":"Assefa F.","year":"2014","journal-title":"Livestock Research for Rural Development"},{"key":"e_1_2_13_16_2","volume-title":"Useful Trees and Shrubs for Ethiopia: Identification, Propagation and Management for 17 Agroclimatic Zones (Technical Manual No. 6)","author":"Bekele-Tesemma A.","year":"2007"},{"key":"e_1_2_13_17_2","first-page":"1353","article-title":"White Sapote (Casimiroa edulis Llave and Lex)","author":"Ahlawat T. 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