{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T08:03:28Z","timestamp":1789545808199,"version":"build-2803163510"},"reference-count":42,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T00:00:00Z","timestamp":1789516800000},"content-version":"vor","delay-in-days":258,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Medicine International"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>\n                    Calf diarrhea is a major constraint to dairy production in Ethiopia, resulting in substantial economic losses and potentially complicated by antimicrobial\u2010resistant bacterial pathogens. This study aimed to determine the isolation of\n                    <jats:italic>Escherichia coli<\/jats:italic>\n                    and\n                    <jats:italic>Salmonella<\/jats:italic>\n                    in diarrheic calves, identify associated risk factors, and assess antimicrobial susceptibility patterns. A cross\u2010sectional study was conducted in calves less than 2\u2009months of age in and around Sebeta Town. The study area and districts were selected purposively, dairy farms were selected by simple random sampling, and diarrheic calves were selected purposively. A total of 129 fecal samples were collected and examined using standard bacteriological techniques and Biolog identification. Antimicrobial susceptibility testing was performed using the disk diffusion method.\n                    <jats:italic>E. coli<\/jats:italic>\n                    and\n                    <jats:italic>Salmonella<\/jats:italic>\n                    were isolated from 65 (50.3%; 95% CI: 41.6\u201359.1) and 8 (6.2%; 95% CI: 1.98\u201310.4) of the 129 samples, respectively. In multivariable logistic regression, sex, age, colostrum feeding, bedding, and housing were significantly associated with increased odds of\n                    <jats:italic>E. coli<\/jats:italic>\n                    isolation. For\n                    <jats:italic>Salmonella<\/jats:italic>\n                    sex, age, and bedding were significantly associated with increased odds of isolation. Most\n                    <jats:italic>E. coli<\/jats:italic>\n                    isolates were susceptible to sulphamethoxazole\u2013trimethoprim (93.85%), polymyxin B (78.46%), gentamicin (76.92%), and ampicillin (73.85%), whereas tetracycline showed the highest resistance (58.46%). Among the 20\u2009\n                    <jats:italic>E. coli<\/jats:italic>\n                    isolates exhibiting resistance to two or more antimicrobial agents, three of twenty (15.0%) fulfilled the predefined multidrug resistance criterion. All\n                    <jats:italic>Salmonella<\/jats:italic>\n                    isolates were susceptible to sulphamethoxazole\u2013trimethoprim and polymyxin B, while 87.5% were susceptible to tetracycline and ampicillin. These findings demonstrate the isolation of\n                    <jats:italic>E. coli<\/jats:italic>\n                    and\n                    <jats:italic>Salmonella<\/jats:italic>\n                    among diarrheic calves and highlight important calf\u2010management factors associated with bacterial isolation, as well as tetracycline resistance among\n                    <jats:italic>E. coli<\/jats:italic>\n                    . Improved calf management, appropriate colostrum feeding, adequate bedding, and prudent antimicrobial use are recommended. Further molecular characterization is warranted to determine the specific diarrheagenic\n                    <jats:italic>E. coli<\/jats:italic>\n                    pathotypes and clarify their contribution to calf diarrhea.\n                  <\/jats:p>","DOI":"10.1155\/vmi\/7166641","type":"journal-article","created":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T07:18:47Z","timestamp":1789543127000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Isolation, Risk Factors, and Antimicrobial Resistance of\n                    <i>Escherichia coli<\/i>\n                    and\n                    <i>Salmonella<\/i>\n                    in Diarrheic Calves in Sebeta, Ethiopia"],"prefix":"10.1155","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7295-264X","authenticated-orcid":false,"given":"Atinafu Regasa","family":"Hailu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6740-9466","authenticated-orcid":false,"given":"Fikru Gizaw","family":"Gurmessa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5248-5925","authenticated-orcid":false,"given":"Teshita Edaso","family":"Bariso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shubisa Abera","family":"Leliso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,16]]},"reference":[{"key":"e_1_2_11_1_2","volume-title":"Ethiopia at a Glance","author":"FAO (Food and Agriculture Organization)","year":"2024"},{"key":"e_1_2_11_2_2","first-page":"181","article-title":"Dairy Production System and Constraints in Ezha Districts of the Gurage Zone, Southern Ethiopia","volume":"12","author":"Bereda A.","year":"2014","journal-title":"Global Veterinaria"},{"key":"e_1_2_11_3_2","volume-title":"Calf Rearing","author":"Thicket B.","year":"2003"},{"key":"e_1_2_11_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0167-5877(97)00059-7"},{"key":"e_1_2_11_5_2","volume-title":"Veterinary Medicine: A Textbook of the Diseases of Cattle, Sheep, Pigs, Goats and Horses","author":"Radostits O. 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