{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T11:31:12Z","timestamp":1774438272421,"version":"3.50.1"},"reference-count":9,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2010,6,21]],"date-time":"2010-06-21T00:00:00Z","timestamp":1277078400000},"content-version":"vor","delay-in-days":171,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Dermatology Research and Practice"],"published-print":{"date-parts":[[2010,1]]},"abstract":"<jats:p>Indeterminate cell histiocytosis (ICH) is a rare proliferative disorder, in which the predominant cells share morphologic and immunophenotypic features from both Langerhans and non\u2010Langerhans cell histiocytosis. We describe a 62\u2010year\u2010old man presenting a 2\u2010month history of firm nodular lesions on the upper lip. Histopathology, immunohistochemical, and ultrastructural analysis showed typical findings of ICH. The patient was treated with thalidomide and almost complete regression of the lesions was reached within 7 months. Nevertheless, one month after remission, he developed an acute myeloid leukemia of the subtype monocytic leukemia (M5). The patient\u2032s condition rapidly worsened and he died due to a respiratory failure four weeks later. We present this case because apart of being rare it joins the effectiveness of thalidomide and the association with an acute monocytic leukemia. A review of the literature is made.<\/jats:p>","DOI":"10.1155\/2010\/569345","type":"journal-article","created":{"date-parts":[[2010,6,21]],"date-time":"2010-06-21T14:35:46Z","timestamp":1277130946000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Indeterminate Cell Histiocytosis in Association with Acute Myeloid Leukemia"],"prefix":"10.1155","volume":"2010","author":[{"given":"Filipa","family":"Ventura","sequence":"first","affiliation":[]},{"given":"Teresa","family":"Pereira","sequence":"additional","affiliation":[]},{"given":"Maria da Luz","family":"Duarte","sequence":"additional","affiliation":[]},{"given":"Herlander","family":"Marques","sequence":"additional","affiliation":[]},{"given":"Fernando","family":"Pardal","sequence":"additional","affiliation":[]},{"given":"Celeste","family":"Brito","sequence":"additional","affiliation":[]}],"member":"311","published-online":{"date-parts":[[2010,6,21]]},"reference":[{"key":"e_1_2_4_1_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2007.07880.x"},{"key":"e_1_2_4_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.0303-6987.2005.00382.x"},{"key":"e_1_2_4_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2006.06.010"},{"key":"e_1_2_4_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1999.tb08470.x"},{"key":"e_1_2_4_5_2","first-page":"525","article-title":"Indeterminate cell histiocytosis\u2014a clinicopathological entity with features of both X- and non-X histiocytosis","volume":"134","author":"Sidoroff A.","year":"1996","journal-title":"British Journal of Dermatology"},{"key":"e_1_2_4_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2005.06644.x"},{"key":"e_1_2_4_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0609.2004.00358.x"},{"key":"e_1_2_4_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(86)70209-0"},{"key":"e_1_2_4_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2007.01.022"}],"container-title":["Dermatology Research and Practice"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/drp\/2010\/569345.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/drp\/2010\/569345.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2010\/569345","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,4]],"date-time":"2024-07-04T14:36:24Z","timestamp":1720103784000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2010\/569345"}},"subtitle":[],"editor":[{"given":"Bernhard W. H.","family":"Zelger","sequence":"additional","affiliation":[]}],"short-title":[],"issued":{"date-parts":[[2010,1]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,1]]}},"alternative-id":["10.1155\/2010\/569345"],"URL":"https:\/\/doi.org\/10.1155\/2010\/569345","archive":["Portico"],"relation":{},"ISSN":["1687-6105","1687-6113"],"issn-type":[{"value":"1687-6105","type":"print"},{"value":"1687-6113","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,1]]},"assertion":[{"value":"2010-03-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2010-05-25","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2010-06-21","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"569345"}}