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Today, with the advent of nanotechnology, the use of light has reached its own dimension where light-matter interactions take place at wavelength and subwavelength scales and where the physical\/chemical nature of nanostructures controls the interactions. This is the field of nanophotonics which allows for the exploration and manipulation of light in and around nanostructures, single molecules, and molecular complexes. What is more is the use of nanophotonics in biomolecular interactions\u2014nanobiophotonics\u2014has prompt for a plethora of molecular diagnostics and therapeutics making use of the remarkable nanoscale properties. In this paper, we shall focus on the uses of nanobiophotonics for molecular diagnostics involving specific sequence characterization of nucleic acids and for gene delivery systems of relevance for therapy strategies. The use of nanobiophotonics for the combined diagnostics\/therapeutics (theranostics) will also be addressed, with particular focus on those systems enabling the development of safer, more efficient, and specific platforms. Finally, the translation of nanophotonics for theranostics into the clinical setting will be discussed.<\/jats:p>","DOI":"10.1155\/2012\/619530","type":"journal-article","created":{"date-parts":[[2011,9,11]],"date-time":"2011-09-11T15:02:11Z","timestamp":1315753331000},"page":"1-11","source":"Crossref","is-referenced-by-count":39,"title":["Nanophotonics for Molecular Diagnostics and Therapy Applications"],"prefix":"10.1155","volume":"2012","author":[{"given":"Jo\u00e3o","family":"Conde","sequence":"first","affiliation":[{"name":"CIGMH, Departamento de Ci\u00eancias da Vida, Faculdade de Ci\u00eancias e Tecnologia, Universidade Nova de Lisboa, Campus de Caparica, 2829-516 Caparica, Portugal"},{"name":"Instituto de Nanociencia de Arag\u00f3n, Universidad de Zaragoza, Campus R\u00edo Ebro, Edif\u00edcio I+D, Mariano Esquillor s\/n, 50018 Zaragoza, Spain"}]},{"given":"Jo\u00e3o","family":"Rosa","sequence":"additional","affiliation":[{"name":"CIGMH, Departamento de Ci\u00eancias da Vida, 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