{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,24]],"date-time":"2025-08-24T01:20:20Z","timestamp":1755998420439,"version":"3.37.3"},"reference-count":19,"publisher":"Wiley","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Critical Care Research and Practice"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p>Respiratory syncytial virus (RSV) lower respiratory tract infection is the most common viral respiratory infection in infants. Several authors have sought to determine which risk factors are the best predictors for severe RSV disease. Our aim was to evaluate if a specific chest radiographic pattern in RSV disease can predict the disease severity. We conducted a multicenter retrospective cohort study in term and preterm neonates with confirmed lower respiratory tract RSV infection, admitted to neonatal intensive care units (NICU) from 2000 to 2010. To determine which factors independently predicted the outcomes, multivariate logistic regression analysis was performed. A total of 259 term and preterm neonates were enrolled. Patients with a consolidation pattern on the chest radiograph at admission (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mrow><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>101<\/mml:mn><\/mml:mrow><\/mml:math>) had greater need for invasive mechanical ventilation (OR: 2.5;<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mrow><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>.015<\/mml:mn><\/mml:mrow><\/mml:math>), respiratory support (OR: 2.3;<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mrow><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>.005<\/mml:mn><\/mml:mrow><\/mml:math>), supplemental oxygen (OR: 3.0;<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mrow><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>.008<\/mml:mn><\/mml:mrow><\/mml:math>), and prolonged stay in the NICU (&gt;7 days) (OR: 1.8;<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\"><mml:mrow><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>.025<\/mml:mn><\/mml:mrow><\/mml:math>). Newborns with a consolidation pattern on admission chest radiograph had a more severe disease course, with greater risk of invasive mechanical ventilation, respiratory support, supplemental oxygen, and prolonged hospitalization.<\/jats:p>","DOI":"10.1155\/2012\/861867","type":"journal-article","created":{"date-parts":[[2012,12,10]],"date-time":"2012-12-10T16:09:46Z","timestamp":1355155786000},"page":"1-6","source":"Crossref","is-referenced-by-count":4,"title":["Value of Chest Radiographic Pattern in RSV Disease of the Newborn: A Multicenter Retrospective Cohort Study"],"prefix":"10.1155","volume":"2012","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2410-2557","authenticated-orcid":true,"given":"Am\u00e9rico","family":"Gon\u00e7alves","sequence":"first","affiliation":[{"name":"Division of Neonatology, S\u00e3o Jo\u00e3o Hospital, Alameda Prof. Hern\u00e2ni Monteiro, 4200-319 Porto, Portugal"}]},{"given":"Gustavo","family":"Rocha","sequence":"additional","affiliation":[{"name":"Division of Neonatology, S\u00e3o Jo\u00e3o Hospital, Alameda Prof. Hern\u00e2ni Monteiro, 4200-319 Porto, Portugal"}]},{"given":"Herc\u00edlia","family":"Guimar\u00e3es","sequence":"additional","affiliation":[{"name":"Division of Neonatology, S\u00e3o Jo\u00e3o Hospital, Alameda Prof. Hern\u00e2ni Monteiro, 4200-319 Porto, Portugal"}]},{"given":"Paula Cristina","family":"Fernandes","sequence":"additional","affiliation":[{"name":"Division of Pediatric and Neonatal Intensive Care, Santo Ant\u00f3nio General Hospital, 4099-001 Porto, Portugal"}]},{"given":"Elisa","family":"Proen\u00e7a","sequence":"additional","affiliation":[{"name":"Unit of Neonatology, J\u00falio Dinis Maternity, 4050-371 Porto, Portugal"}]},{"given":"Dulce","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Unit of Neonatology, J\u00falio Dinis Maternity, 4050-371 Porto, Portugal"}]},{"given":"Paula","family":"Rocha","sequence":"additional","affiliation":[{"name":"Unit of Neonatology, M\u00aaPia Children's Hospital, 4050-311 Porto, Portugal"}]},{"given":"Concei\u00e7\u00e3o","family":"Quintas","sequence":"additional","affiliation":[{"name":"Unit of Neonatology, Vila Nova de Gaia Hospital, 4434-502 Vila Nova de Gaia, Portugal"}]},{"given":"Teresa","family":"Martins","sequence":"additional","affiliation":[{"name":"Unit of Neonatology, Pedro Hispano Hospital, 4454-509 Matosinhos, Portugal"}]},{"given":"Alice","family":"Freitas","sequence":"additional","affiliation":[{"name":"Unit of Neonatology, Senhora da Oliveira Hospital, 4835-044 Guimar\u00e3es, Portugal"}]},{"given":"Clara Paz","family":"Dias","sequence":"additional","affiliation":[{"name":"Unit of Neonatology, Senhora da Oliveira Hospital, 4835-044 Guimar\u00e3es, Portugal"}]},{"given":"Albina","family":"Ramires","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Braga Hospital, 4710-243 Braga, Portugal"}]}],"member":"311","reference":[{"issue":"5","key":"1","doi-asserted-by":"crossref","first-page":"S127","DOI":"10.1067\/S0022-3476(03)00510-9","volume":"143","year":"2003","journal-title":"Journal of Pediatrics"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/S1526-0542(09)70012-0"},{"issue":"2","key":"3","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1007\/BF02386634","volume":"16","year":"1986","journal-title":"Pediatric Radiology"},{"issue":"3","key":"4","first-page":"209","volume":"48","year":"2003","journal-title":"Respiratory Care"},{"issue":"5","key":"5","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1136\/adc.71.5.463","volume":"71","year":"1994","journal-title":"Archives of Disease in Childhood"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2431-9-56"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.21026"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1542\/peds.104.4.894"},{"issue":"2","key":"9","first-page":"S2","volume":"135","year":"1999","journal-title":"Journal of Pediatrics"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(95)70547-3"},{"issue":"12","key":"11","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1097\/00003246-199012000-00009","volume":"18","year":"1990","journal-title":"Critical Care Medicine"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1007\/s003300100887"},{"issue":"2","key":"13","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1111\/j.1651-2227.1990.tb11442.x","volume":"79","year":"1990","journal-title":"Acta Paediatrica Scandinavica"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.1039"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2011.02181.x"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-008-1042-3"},{"issue":"8","key":"17","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1080\/080352500750043387","volume":"89","year":"2000","journal-title":"Acta Paediatrica, International Journal of Paediatrics"},{"key":"18","doi-asserted-by":"crossref","first-page":"1723","DOI":"10.1164\/ajrccm.163.7.2011060","volume":"163","year":"2001","journal-title":"American Journal of Respiratory and Critical Care Medicine"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1542\/peds.112.6.1442"}],"container-title":["Critical Care Research and Practice"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/ccrp\/2012\/861867.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ccrp\/2012\/861867.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ccrp\/2012\/861867.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,20]],"date-time":"2017-06-20T23:55:43Z","timestamp":1498002943000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/ccrp\/2012\/861867\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":19,"alternative-id":["861867","861867"],"URL":"https:\/\/doi.org\/10.1155\/2012\/861867","relation":{},"ISSN":["2090-1305","2090-1313"],"issn-type":[{"type":"print","value":"2090-1305"},{"type":"electronic","value":"2090-1313"}],"subject":[],"published":{"date-parts":[[2012]]}}}