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The presence of secondary deposits in the liver significantly increases the morbidity and mortality in these patients. The only potentially curative treatment is the surgical resection of the primary tumor and hepatic lesions. However, only 10% of patients presents under ideal conditions for that approach. Several techniques aimed at localized liver lesions have been applied also with interesting results in terms of survival and symptom control. The same has been demonstrated with new systemic therapies (target therapies). However, these are still under study, in order to define their true role in the management of these patients. This paper intends to address, in a general way, the various treatment options in patients with liver metastases from neuroendocrine tumors.<\/jats:p>","DOI":"10.1155\/2013\/702167","type":"journal-article","created":{"date-parts":[[2013,2,14]],"date-time":"2013-02-14T21:08:38Z","timestamp":1360876118000},"page":"1-9","source":"Crossref","is-referenced-by-count":3,"title":["The Treatment of Liver Metastases in Patients with Neuroendocrine Tumors in 2012"],"prefix":"10.1155","volume":"2013","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9681-1224","authenticated-orcid":true,"given":"Daniela","family":"Macedo","sequence":"first","affiliation":[{"name":"Oncology Division, Hospital de Santa Maria, Lisbon, Portugal"}]},{"given":"Teresa","family":"Amaral","sequence":"additional","affiliation":[{"name":"Oncology Division, Hospital de Santa Maria, Lisbon, Portugal"}]},{"given":"Isabel","family":"Fernandes","sequence":"additional","affiliation":[{"name":"Oncology Division, Hospital de Santa 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