{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T01:27:44Z","timestamp":1774488464462,"version":"3.50.1"},"reference-count":55,"publisher":"Wiley","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100005672","name":"Funda\u00e7\u00e3o de Apoio ao Desenvolvimento do Ensino, Ci\u00eancia e Tecnologia do Estado de Mato Grosso do Sul","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005672","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Evidence-Based Complementary and Alternative Medicine"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p>Propolis from stingless bees<jats:italic>Tetragonisca fiebrigi<\/jats:italic>found in Brazil is used in folk medicine by their nutritional and therapeutic properties. However, there are no scientific records evidencing such properties. The present study was designed to investigate the chemical composition and the biological properties of propolis from<jats:italic>T. fiebrigi<\/jats:italic>. For this, the chemical composition of the ethanol extract of propolis (EEP) was determined by GC-MS and presented phenolic compounds, alcohol, and terpenes as its major class compounds. The antimicrobial activity was accessed in gram-positive and gram-negative bacteria and in fungi, isolated from different biological fluids and reference strains. The EEP was active against all microorganisms and showed antioxidant activity by scavenging free radicals, inhibiting hemolysis and lipid peroxidation in human erythrocytes incubated with an oxidizing agent. The anti-inflammatory potential of the EEP was confirmed by inhibition of the hyaluronidase enzyme. The cytotoxic activity was concentration-dependent against K562 cells, with a predominance of death by necrosis. Taken together, these results show that propolis from<jats:italic>T. fiebrigi<\/jats:italic>has important therapeutic activities, which suggest its potential application in the pharmaceutical industry, as well as in health foods, beverages, and nutritional supplements.<\/jats:p>","DOI":"10.1155\/2015\/296186","type":"journal-article","created":{"date-parts":[[2015,6,22]],"date-time":"2015-06-22T17:01:52Z","timestamp":1434992512000},"page":"1-11","source":"Crossref","is-referenced-by-count":111,"title":["Antimicrobial, Antioxidant, Anti-Inflammatory, and Cytotoxic Activities of Propolis from the Stingless Bee<i>Tetragonisca fiebrigi<\/i>(Jata\u00ed)"],"prefix":"10.1155","volume":"2015","author":[{"given":"Jaqueline Ferreira","family":"Campos","sequence":"first","affiliation":[{"name":"School of Environmental and Biological Science, Federal University of Grande Dourados, Rodovia Dourados-Itahum, Km 12, 79804-970 Dourados, MS, Brazil"}]},{"given":"Uilson Pereira 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