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Cytokines can be aberrantly produced by cancer and immune system cells and are of particular relevance in pain. Currently, there are very few strategies to control the release of cytokines that seems to be related to cancer pain. Nevertheless, in some cases, targeted drugs are available and in use for other diseases. In this paper, we aim to review the importance of cytokines in cancer pain and targeted strategies that can have an impact on controlling this symptom.<\/jats:p>","DOI":"10.1155\/2015\/984570","type":"journal-article","created":{"date-parts":[[2015,10,12]],"date-time":"2015-10-12T23:19:56Z","timestamp":1444691996000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":46,"title":["Treatment of Cancer Pain by Targeting Cytokines"],"prefix":"10.1155","volume":"2015","author":[{"given":"I.","family":"Vendrell","sequence":"first","affiliation":[]},{"given":"D.","family":"Macedo","sequence":"additional","affiliation":[]},{"given":"I.","family":"Alho","sequence":"additional","affiliation":[]},{"given":"M. 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