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This study is aimed at identifying the best performing algorithm and the most relevant characteristics to categorise individuals with HIV\/AIDS at high risk of dementia from the application of data mining. Principal component analysis (PCA) algorithm was used and tested comparatively between the following machine learning algorithms: logistic regression, decision tree, neural network, KNN, and random forest. The database used for this study was built from the data collection of 270 individuals infected with HIV\/AIDS and followed up at the outpatient clinic of a reference hospital for infectious and parasitic diseases in the State of Cear\u00e1, Brazil, from January to April 2019. Also, the performance of the algorithms was analysed for the 104 characteristics available in the database; then, with the reduction of dimensionality, there was an improvement in the quality of the machine learning algorithms and identified that during the tests, even losing about 30% of the variation. Besides, when considering only 23 characteristics, the precision of the algorithms was 86% in random forest, 56% logistic regression, 68% decision tree, 60% KNN, and 59% neural network. The random forest algorithm proved to be more effective than the others, obtaining 84% precision and 86% accuracy.<\/jats:p>","DOI":"10.1155\/2021\/4602465","type":"journal-article","created":{"date-parts":[[2021,7,10]],"date-time":"2021-07-10T19:35:08Z","timestamp":1625945708000},"page":"1-8","source":"Crossref","is-referenced-by-count":11,"title":["Application of Data Mining Algorithms for Dementia in People with HIV\/AIDS"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3128-6000","authenticated-orcid":true,"given":"Luana Ibiapina Cordeiro Cal\u00edope","family":"Pinheiro","sequence":"first","affiliation":[{"name":"Graduate Program in Clinical Care in Nursing and Health, State University of Cear\u00e1, Fortaleza, Brazil"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7685-6169","authenticated-orcid":true,"given":"Maria L\u00facia Duarte","family":"Pereira","sequence":"additional","affiliation":[{"name":"Graduate Program in Clinical Care in Nursing and Health, State University of Cear\u00e1, Fortaleza, Brazil"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3332-6253","authenticated-orcid":true,"given":"Marcial Porto","family":"Fernandez","sequence":"additional","affiliation":[{"name":"Graduate Program in Computer Science, State University of Cear\u00e1, Fortaleza, Brazil"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2410-7449","authenticated-orcid":true,"given":"Francisco Mard\u00f4nio Vieira","family":"Filho","sequence":"additional","affiliation":[{"name":"Graduate Program in Computer Science, State University of Cear\u00e1, Fortaleza, Brazil"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0847-824X","authenticated-orcid":true,"given":"Wilson Jorge Correia Pinto","family":"de Abreu","sequence":"additional","affiliation":[{"name":"Porto School of Nursing, Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1191-6930","authenticated-orcid":true,"given":"Pedro Gabriel Cal\u00edope Dantas","family":"Pinheiro","sequence":"additional","affiliation":[{"name":"Graduate Program in Applied Informatics, University of Fortaleza, Fortaleza, Brazil"}]}],"member":"311","reference":[{"doi-asserted-by":"publisher","key":"1","DOI":"10.2967\/jnumed.118.219097"},{"doi-asserted-by":"publisher","key":"2","DOI":"10.1093\/bioinformatics\/btz602"},{"doi-asserted-by":"publisher","key":"3","DOI":"10.29193\/RMU.35.3.1"},{"doi-asserted-by":"publisher","key":"4","DOI":"10.1155\/2012\/467154"},{"doi-asserted-by":"publisher","key":"5","DOI":"10.1590\/1980-549720200020"},{"doi-asserted-by":"publisher","key":"6","DOI":"10.1038\/nrneurol.2016.27"},{"issue":"1","key":"7","first-page":"1","article-title":"Atualiza\u00e7\u00f5es sobre dem\u00eancia cortical em indiv\u00edduos infectados pelo HIV","volume":"12","author":"D. 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