{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T08:27:10Z","timestamp":1768552030266,"version":"3.49.0"},"reference-count":33,"publisher":"Wiley","license":[{"start":{"date-parts":[[2022,11,19]],"date-time":"2022-11-19T00:00:00Z","timestamp":1668816000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"European Union\u2019s Horizon 2020 Research and Innovation Programme","award":["777167"],"award-info":[{"award-number":["777167"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Breast Journal"],"published-print":{"date-parts":[[2022,11,19]]},"abstract":"<jats:p>Background. Identifying and understanding modifiable factors for the well-being of cancer patients is critical in survivorship research. We studied variables associated with the exercise habits of breast cancer patients and investigated if the achievement of exercise recommendations was associated with enhanced quality of life and\/or psychological well-being. Material and Methods. 311 women from Finland, Portugal, Israel, and Italy receiving adjuvant therapy for stage I\u2013III breast cancer answered questions about sociodemographic factors and physical exercise. Quality of life was assessed by the EORTC C30 and BR23 questionnaires. Anxiety and depression were evaluated using the HADS scale. Results. At the beginning of adjuvant therapy and after twelve months, 32% and 26% of participants were physically inactive, 27% and 30% exercised between 30 and 150 minutes per week, while 41% and 45% exercised the recommended 150 minutes or more per week. Relative to other countries, Finnish participants were more likely to be active at baseline and at twelve months (89% vs. 50%, <jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mi>p<\/a:mi>\n                        <a:mo>&lt;<\/a:mo>\n                        <a:mn>0.001<\/a:mn>\n                     <\/a:math>\n                  <\/jats:inline-formula> and 87% vs. 64%, <jats:inline-formula>\n                     <c:math xmlns:c=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                        <c:mi>p<\/c:mi>\n                        <c:mo>&lt;<\/c:mo>\n                        <c:mn>0.001<\/c:mn>\n                     <\/c:math>\n                  <\/jats:inline-formula>). Participants with stage I cancer were more likely to be active at twelve months than those with a higher stage (80% vs. 70%,<jats:inline-formula>\n                     <e:math xmlns:e=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                        <e:mi>p<\/e:mi>\n                        <e:mo>&lt;<\/e:mo>\n                        <e:mn>0.05<\/e:mn>\n                     <\/e:math>\n                  <\/jats:inline-formula>). The inactive participants reported more anxiety (<jats:inline-formula>\n                     <g:math xmlns:g=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\">\n                        <g:mi>p<\/g:mi>\n                        <g:mo>&lt;<\/g:mo>\n                        <g:mn>0.05<\/g:mn>\n                     <\/g:math>\n                  <\/jats:inline-formula>) and depression (<jats:inline-formula>\n                     <i:math xmlns:i=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\">\n                        <i:mi>p<\/i:mi>\n                        <i:mo>&lt;<\/i:mo>\n                        <i:mn>0.001<\/i:mn>\n                     <\/i:math>\n                  <\/jats:inline-formula>), lower global quality of life (<jats:inline-formula>\n                     <k:math xmlns:k=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M6\">\n                        <k:mi>p<\/k:mi>\n                        <k:mo>&lt;<\/k:mo>\n                        <k:mn>0.001<\/k:mn>\n                     <\/k:math>\n                  <\/jats:inline-formula>), and more side effects (<jats:inline-formula>\n                     <m:math xmlns:m=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M7\">\n                        <m:mi>p<\/m:mi>\n                        <m:mo>&lt;<\/m:mo>\n                        <m:mn>0.05<\/m:mn>\n                     <\/m:math>\n                  <\/jats:inline-formula>) than the others at twelve months. Accordingly, those who remained inactive or decreased their level of exercise from baseline to twelve months reported more anxiety (<jats:inline-formula>\n                     <o:math xmlns:o=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M8\">\n                        <o:mi>p<\/o:mi>\n                        <o:mo>&lt;<\/o:mo>\n                        <o:mn>0.01<\/o:mn>\n                     <\/o:math>\n                  <\/jats:inline-formula>) and depression (<jats:inline-formula>\n                     <q:math xmlns:q=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M9\">\n                        <q:mi>p<\/q:mi>\n                        <q:mo>&lt;<\/q:mo>\n                        <q:mn>0.001<\/q:mn>\n                     <\/q:math>\n                  <\/jats:inline-formula>), lower global quality of life (<jats:inline-formula>\n                     <s:math xmlns:s=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M10\">\n                        <s:mi>p<\/s:mi>\n                        <s:mo>&lt;<\/s:mo>\n                        <s:mn>0.001<\/s:mn>\n                     <\/s:math>\n                  <\/jats:inline-formula>), and more side effects (<jats:inline-formula>\n                     <u:math xmlns:u=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M11\">\n                        <u:mi>p<\/u:mi>\n                        <u:mo>&lt;<\/u:mo>\n                        <u:mn>0.05<\/u:mn>\n                     <\/u:math>\n                  <\/jats:inline-formula>) than those with the same or increased level of exercise. Conclusion. For women with early breast cancer, exercise was associated with a better quality of life, less depression and anxiety, and fewer adverse events of adjuvant therapy. Trial registration number: NCT05095675. Paula Poikonen-Saksela on behalf of Bounce consortium (https:\/\/www.bounce-project.eu\/). <\/jats:p>","DOI":"10.1155\/2022\/9921575","type":"journal-article","created":{"date-parts":[[2022,11,19]],"date-time":"2022-11-19T15:20:09Z","timestamp":1668871209000},"page":"1-8","source":"Crossref","is-referenced-by-count":14,"title":["Associations between Physical Exercise, Quality of Life, Psychological Symptoms and Treatment Side Effects in Early Breast Cancer"],"prefix":"10.1155","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0123-1313","authenticated-orcid":true,"given":"Leena","family":"Vehmanen","sequence":"first","affiliation":[{"name":"Helsinki University Hospital Comprehensive Cancer Center and University of Helsinki, Helsinki, Finland"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9719-9110","authenticated-orcid":true,"given":"Johanna","family":"Mattson","sequence":"additional","affiliation":[{"name":"Helsinki University Hospital Comprehensive Cancer Center and University of Helsinki, Helsinki, Finland"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0802-5213","authenticated-orcid":true,"given":"Evangelos","family":"Karademas","sequence":"additional","affiliation":[{"name":"Department of Psychology, University of Crete, Rethymno, Greece"},{"name":"Foundation for Research and Technology-Hellas, Institute of Computer Science, Heraklion, Greece"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5071-3007","authenticated-orcid":true,"given":"Albino J.","family":"Oliveira-Maia","sequence":"additional","affiliation":[{"name":"Champalimaud Research & Clinical Centre, Champalimaud Foundation, Lisboa, Portugal"},{"name":"NOVA Medical School NMS, Universidade Nova de Lisboa, Lisboa, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2287-4799","authenticated-orcid":true,"given":"Berta","family":"Sousa","sequence":"additional","affiliation":[{"name":"Breast Unit, Champalimaud Clinical Centre\/Champalimaud Foundation, Lisboa, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5589-8837","authenticated-orcid":true,"given":"Ruth","family":"Pat-Horenczyk","sequence":"additional","affiliation":[{"name":"School of Social Work and Social Welfare, The Hebrew University of Jerusalem, Jerusalem, Israel"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1382-6779","authenticated-orcid":true,"given":"Ketti","family":"Mazzocco","sequence":"additional","affiliation":[{"name":"Applied Research Division for Cognitive and Psychological Science, European Institute of Oncology IRCCS, Milan, Italy"},{"name":"Department of Oncology and Hemato-oncology, University of Milan, Milan, Italy"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0116-8564","authenticated-orcid":true,"given":"Panagiotis","family":"Simos","sequence":"additional","affiliation":[{"name":"Foundation for Research and Technology-Hellas, Institute of Computer Science, Heraklion, Greece"},{"name":"School of Medicine, University of Crete, Rethymno, Greece"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6692-2249","authenticated-orcid":true,"given":"F\u00e1tima","family":"Cardoso","sequence":"additional","affiliation":[{"name":"Breast Unit, Champalimaud Clinical Centre\/Champalimaud Foundation, Lisboa, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8936-6938","authenticated-orcid":true,"given":"Greta","family":"Pettini","sequence":"additional","affiliation":[{"name":"Applied Research Division for Cognitive and Psychological Science, European Institute of Oncology IRCCS, Milan, Italy"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7761-2804","authenticated-orcid":true,"given":"Chiara","family":"Marzorati","sequence":"additional","affiliation":[{"name":"Applied Research Division for Cognitive and Psychological Science, European Institute of Oncology IRCCS, Milan, Italy"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8455-2918","authenticated-orcid":true,"given":"Eleni","family":"Kolokotroni","sequence":"additional","affiliation":[{"name":"In Silico Oncology and In Silico Medicine Group, Institute of Communication and Computer Systems, School of Electrical and Computer Engineering, National Technical University of Athens, Athens, Greece"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2054-477X","authenticated-orcid":true,"given":"Georgios","family":"Stamatakos","sequence":"additional","affiliation":[{"name":"In Silico Oncology and In Silico Medicine Group, Institute of Communication and Computer Systems, School of Electrical and Computer Engineering, National Technical University of Athens, Athens, Greece"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6057-205X","authenticated-orcid":true,"given":"Diana","family":"Frasquilho","sequence":"additional","affiliation":[{"name":"Breast Unit, Champalimaud Clinical Centre\/Champalimaud Foundation, Lisboa, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2274-1937","authenticated-orcid":true,"given":"Paula","family":"Poikonen-Saksela","sequence":"additional","affiliation":[{"name":"Helsinki University Hospital Comprehensive Cancer Center and University of Helsinki, Helsinki, Finland"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(16)31891-8"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2015.10.063"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1111\/ecc.13037"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.3109\/0284186x.2014.998275"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/j.bulcan.2020.06.013"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdu012"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/j.breast.2019.02.001"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1186\/s13058-018-1051-6"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1002\/pon.1728"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1007\/s12160-010-9225-1"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports-2017-098285"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD005001.pub3"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD011292.pub2"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1016\/j.breast.2017.02.002"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-018-4363-2"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.21873\/invivo.11554"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.29383"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0030955"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1249\/MSS.0b013e3181e0c112"},{"key":"20","volume-title":"Physical Activity Guidelines Advisory Committee Report","author":"Physical Activities Guidelines Advisory Committee","year":"2008"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports-2020-102955"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2021.6590"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/85.5.365"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1200\/jco.1996.14.10.2756"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.1983.tb09716.x"},{"issue":"9","key":"26","first-page":"3875","article-title":"Effectiveness of a 12-month exercise program on physical performance and quality of life of breast cancer survivors","volume":"32","author":"T. Saarto","year":"2012","journal-title":"Anticancer Research"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.11227"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.1136\/bmjsem-2020-000960"},{"key":"29","doi-asserted-by":"publisher","DOI":"10.1207\/s15324796abm2404_02"},{"key":"30","doi-asserted-by":"publisher","DOI":"10.1186\/s13063-016-1487-x"},{"key":"31","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13020264"},{"key":"32","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2020.00546"},{"key":"33","doi-asserted-by":"publisher","DOI":"10.3390\/cancers11050706"}],"container-title":["The Breast Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/tbj\/2022\/9921575.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/tbj\/2022\/9921575.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/tbj\/2022\/9921575.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,19]],"date-time":"2022-11-19T15:20:14Z","timestamp":1668871214000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/tbj\/2022\/9921575\/"}},"subtitle":[],"editor":[{"given":"Pranshu","family":"Sahgal","sequence":"additional","affiliation":[]}],"short-title":[],"issued":{"date-parts":[[2022,11,19]]},"references-count":33,"alternative-id":["9921575","9921575"],"URL":"https:\/\/doi.org\/10.1155\/2022\/9921575","relation":{},"ISSN":["1524-4741","1075-122X"],"issn-type":[{"value":"1524-4741","type":"electronic"},{"value":"1075-122X","type":"print"}],"subject":[],"published":{"date-parts":[[2022,11,19]]}}}