{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T01:12:02Z","timestamp":1760404322716},"reference-count":0,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Analytical Methods in Chemistry"],"published-print":{"date-parts":[[2000,1]]},"abstract":"<jats:p>A low inner volume (ca. 64 ml) probe was built up in an injector\u2010commutator in order to behave as a photometric leaping detector in flow analysis. It comprises a bicolour light\u2010emitting diode (BLED), as a source of pulsed radiation in the red and green visible region, and two phototransistors as transducers. Sample injection, detector relocation, analytical signal recording, data treatment and definition of the spectral working range were computer\u2010controlled. The feasibility of the system was initially demonstrated in the flow\u2010injection speciation of iron, and the overall standard deviation of results was estimated as \u00b1 1.6 and \u00b1 1.4% for 1.6\u20134.0 mg l<jats:sup>\u22121<\/jats:sup> Fe(II) or total iron after eightfold processing of synthetic samples. The system was further applied to drug analysis: the mean deviations of results for typical samples were estimated as \u00b1 5.2 and \u00b1 3.3%, and the relative standard deviation as \u00b1 1.6 and \u00b1 1.3% for Fe(II) and total iron, respectively. Results were compared with those obtained by a conventional spectrophotometric procedure and no statistic differences at the 95% confidence level were found. In relation to an earlier system with multi\u2010site detection, the proposed system is more stable, presenting low drift with a relative standard deviation of 0.026% and 0.039% for measurements (n=120 during 4 h of observation) with green and red emission. It is also faster with a sampling rate of 133 h<jats:sup>\u22121<\/jats:sup> and carryover problems are not found. The possibility of compensating the Schlieren noise by dual\u2010wavelength spectrophotometry is discussed.<\/jats:p>","DOI":"10.1155\/s1463924600000092","type":"journal-article","created":{"date-parts":[[2007,3,8]],"date-time":"2007-03-08T08:53:36Z","timestamp":1173344016000},"page":"83-88","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["An improved leaping detector for flow analysis applied to iron speciation in drugs"],"prefix":"10.1155","volume":"22","author":[{"given":"S\u00e9rgio R. B.","family":"Santos","sequence":"first","affiliation":[]},{"given":"M\u00e1rio C. U.","family":"Ara\u00fajo","sequence":"additional","affiliation":[]},{"given":"Ricardo S.","family":"Honorato","sequence":"additional","affiliation":[]},{"given":"Elias A. G.","family":"Zagatto","sequence":"additional","affiliation":[]},{"given":"Jos\u00e9 F. C.","family":"Lima","sequence":"additional","affiliation":[]},{"given":"Rui A. S.","family":"Lapa","sequence":"additional","affiliation":[]}],"member":"311","published-online":{"date-parts":[[2000,1]]},"container-title":["Journal of Analytical Methods in Chemistry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/jamc\/2000\/145645.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/S1463924600000092","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T23:14:50Z","timestamp":1723072490000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/S1463924600000092"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,1]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2000,1]]}},"alternative-id":["10.1155\/S1463924600000092"],"URL":"https:\/\/doi.org\/10.1155\/s1463924600000092","archive":["Portico"],"relation":{},"ISSN":["2090-8865","2090-8873"],"issn-type":[{"type":"print","value":"2090-8865"},{"type":"electronic","value":"2090-8873"}],"subject":[],"published":{"date-parts":[[2000,1]]},"assertion":[{"value":"2000-01-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}