{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T05:46:09Z","timestamp":1761630369339,"version":"3.32.0"},"reference-count":40,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2005,3,1]],"date-time":"2005-03-01T00:00:00Z","timestamp":1109635200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina Cl\u00ednica"],"published-print":{"date-parts":[[2005,3]]},"DOI":"10.1157\/13072569","type":"journal-article","created":{"date-parts":[[2005,3,14]],"date-time":"2005-03-14T18:11:22Z","timestamp":1110823882000},"page":"361-367","source":"Crossref","is-referenced-by-count":8,"title":["Factores pron\u00f3sticos en el melanoma maligno cut\u00e1neo localizado: estudio de 639 pacientes"],"prefix":"10.1016","volume":"124","author":[{"given":"Eduardo","family":"Nagore Engu\u00eddanos","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vicente","family":"Oliver Mart\u00ednez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafael","family":"Botella Estrada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amelia","family":"Insa Moll\u00e1","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Miguel","family":"Fortea Baixauli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1157\/13072569_bib1","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1111\/j.1365-2559.1983.tb02279.x","article-title":"Prognosis in patients with thin malignant melanoma: influence of regression","volume":"7","author":"McGovern","year":"1983","journal-title":"Histopathology"},{"key":"10.1157\/13072569_bib2","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1093\/jnci\/86.10.761","article-title":"Clinical and histopathologic predictors of survival in patients with malignant melanoma: a population-based study in Sweden","volume":"86","author":"Th\u00f6rn","year":"1994","journal-title":"J Natl Cancer Inst"},{"key":"10.1157\/13072569_bib3","doi-asserted-by":"crossref","first-page":"3622","DOI":"10.1200\/JCO.2001.19.16.3622","article-title":"Prognostic factors analysis of 17,600 melanoma patients: validation of the American Joint Committee on Cancer Melanoma Staging System","volume":"19","author":"Balch","year":"2001","journal-title":"J Clin Oncol"},{"key":"10.1157\/13072569_bib4","first-page":"175","article-title":"Regional non-nodal metastases of cutaneous melanoma","volume":"12","author":"Cascinelli","year":"1986","journal-title":"Eur J Surg Cancer"},{"key":"10.1157\/13072569_bib5","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1097\/00000658-198107000-00019","article-title":"Malignant melanoma: the prognostic significance of \u00abmicroscopic satellites \u00bb in the reticular dermis and subcutaneous fat","volume":"194","author":"Day","year":"1981","journal-title":"Ann Surg"},{"key":"10.1157\/13072569_bib6","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.1001\/archsurg.1991.01410360031006","article-title":"The prognostic implications of microscopic satellites in patients with clinical stage I melanoma","volume":"194","author":"Leon","year":"1991","journal-title":"Arch Surg"},{"key":"10.1157\/13072569_bib7","doi-asserted-by":"crossref","first-page":"2183","DOI":"10.1002\/1097-0142(19840515)53:10<2183::AID-CNCR2820531029>3.0.CO;2-9","article-title":"Microscopic satellites are more highly associated with regional lymph node metastases than with primary melanoma thickness","volume":"53","author":"Harrist","year":"1984","journal-title":"Cancer"},{"key":"10.1157\/13072569_bib8","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1067\/msy.2002.127546","article-title":"A long-term analysis of 1018 patients with melanoma by classic Cox regresssion and tree-structured survival analysis at a major referral center: Implications on the future of cancer staging","volume":"132","author":"Averbook","year":"2002","journal-title":"Surgery"},{"key":"10.1157\/13072569_bib9","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1097\/00008390-200110000-00001","article-title":"Prognostic factors in invasive cutaneous malignant melanoma: a population-based study and review","volume":"11","author":"Masback","year":"2001","journal-title":"Melanoma Res"},{"key":"10.1157\/13072569_bib10","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/0190-9622(92)70068-Q","article-title":"Influence of gender on survival in patients with stage I malignant melanoma","volume":"26","author":"Vossaert","year":"1992","journal-title":"J Am Acad Dermatol"},{"key":"10.1157\/13072569_bib11","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1002\/(SICI)1097-0142(19960401)77:7<1303::AID-CNCR12>3.0.CO;2-5","article-title":"Prognostic value of tumor infiltrating lymphocytes in the vertical growth phase of primary cutaneous melanoma","volume":"77","author":"Clemente","year":"1996","journal-title":"Cancer"},{"key":"10.1157\/13072569_bib12","doi-asserted-by":"crossref","first-page":"1488","DOI":"10.1002\/cncr.11196","article-title":"Tumor mitotic rate is a more powerful prognostic indicator than ulceration in patients with primary cutaneous melanoma. An analysis of 3661 patients from a single center","volume":"97","author":"Azzola","year":"2003","journal-title":"Cancer"},{"key":"10.1157\/13072569_bib13","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1038\/bjc.1995.35","article-title":"Prognostic models for subgroups of melanoma patients from the Scottish Melanoma Group database: 1979-86, and their subsequent validation","volume":"71","author":"MacKie","year":"1995","journal-title":"Br J Cancer"},{"key":"10.1157\/13072569_bib14","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.1002\/1097-0142(19831001)52:7<1330::AID-CNCR2820520732>3.0.CO;2-M","article-title":"Malignant melanoma of the skin. I. The association of tumor depth and type, and patient sex, age, and site with survival","volume":"52","author":"Blois","year":"1983","journal-title":"Cancer"},{"key":"10.1157\/13072569_bib15","first-page":"383","article-title":"Malignant melanoma. A multivariate analysis of prognostic factors","volume":"24","author":"Vollmer","year":"1989","journal-title":"Pathol Annu"},{"key":"10.1157\/13072569_bib16","unstructured":"McGovern VJ, Shaw HM, Milton GW, Farago GA. Lymphocytic infiltration and survival in malignant melanoma. En: Ackerman AB, editor. Pathology of malignant melanoma. New York: 1981; p. 341."},{"key":"10.1157\/13072569_bib17","doi-asserted-by":"crossref","first-page":"2391","DOI":"10.1002\/(SICI)1097-0142(19990601)85:11<2391::AID-CNCR14>3.0.CO;2-I","article-title":"Can immunohistochemical markers and mitotic rate improve prognostic precision in patients with primary melanoma?","volume":"85","author":"Ostmeier","year":"1999","journal-title":"Cancer"},{"key":"10.1157\/13072569_bib18","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1097\/00008390-200202000-00009","article-title":"Differentially expressed genes identified in human melanoma cell lines with different metastatic behaviour using high density oligonucleotide arrays","volume":"12","author":"De Wit","year":"2002","journal-title":"Melanoma Res"},{"key":"10.1157\/13072569_bib19","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1002\/(SICI)1097-0215(19981029)78:3<315::AID-IJC10>3.0.CO;2-5","article-title":"Prognostic factors for cutaneous malignant melanoma in Vaud, Switzerland","volume":"78","author":"Levi","year":"1998","journal-title":"Int J Cancer"},{"key":"10.1157\/13072569_bib20","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1002\/ijc.2910430303","article-title":"Pathologic prognostic factors for cutaneous malignant melanoma: the Western Canada Melanoma Study","volume":"43","author":"Worth","year":"1989","journal-title":"Int J Cancer"},{"key":"10.1157\/13072569_bib21","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/0277-5379(83)90421-2","article-title":"Low- and high-risk malignant melanoma \u2013 I. Evaluation of clinical and histological prognosticators in 585 cases","volume":"19","author":"Schmoeckel","year":"1983","journal-title":"Eur J Cancer"},{"key":"10.1157\/13072569_bib22","first-page":"343","article-title":"A multifactorial analysis of melanoma. II. Prognostic factors in patients with stage I (localized) melanoma","volume":"86","author":"Balch","year":"1979","journal-title":"Surgery"},{"key":"10.1157\/13072569_bib23","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1002\/1097-0142(19900115)65:2<362::AID-CNCR2820650231>3.0.CO;2-E","article-title":"Malignant melanoma. Changing trends in factors influencing metastasis-free survival from 1964 to 1982","volume":"65","author":"Drzewiecki","year":"1990","journal-title":"Cancer"},{"key":"10.1157\/13072569_bib24","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1002\/(SICI)1097-0142(19960801)78:3<427::AID-CNCR8>3.0.CO;2-G","article-title":"Predicting five-year outcome for patients with cutaneous melanoma in a population-based study","volume":"78","author":"Barnhill","year":"1996","journal-title":"Cancer"},{"key":"10.1157\/13072569_bib25","doi-asserted-by":"crossref","first-page":"3635","DOI":"10.1200\/JCO.2001.19.16.3635","article-title":"Final version of the American Joint Committee on Cancer staging system for cutaneous melanoma","volume":"19","author":"Balch","year":"2001","journal-title":"J Clin Oncol"},{"key":"10.1157\/13072569_bib26","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1111\/j.1365-2559.1984.tb02388.x","article-title":"Inter-observer variation between pathologists in the classification of cutaneous malignant melanoma in Western Australia","volume":"8","author":"Heenan","year":"1984","journal-title":"Histopathology"},{"key":"10.1157\/13072569_bib27","first-page":"110","article-title":"Aspectos controvertidos en el melanoma maligno cut\u00e1neo","volume":"101","author":"Ord\u00f3\u00f1ez Gallego","year":"1993","journal-title":"Med Clin (Barc)"},{"key":"10.1157\/13072569_bib28","series-title":"Cutaneous melanoma","first-page":"103","article-title":"Histopathology and precursor lesions","author":"Barnhill","year":"1998"},{"key":"10.1157\/13072569_bib29","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1097\/00000658-197011000-00017","article-title":"Thickness, cross-sectional areas and depth of invasion in the prognosis of cutaneous melanoma","volume":"172","author":"Breslow","year":"1970","journal-title":"Ann Surg"},{"key":"10.1157\/13072569_bib30","first-page":"705","article-title":"The histogenesis and biologic behavior of primary human malignant melanomas of the skin","volume":"29","author":"Clark","year":"1969","journal-title":"Cancer Res"},{"key":"10.1157\/13072569_bib31","doi-asserted-by":"crossref","first-page":"12","DOI":"10.3109\/00313028609090822","article-title":"The classification of malignant melanoma, its histological reporting and registration: a revision of the 1972 classification","volume":"18","author":"McGovern","year":"1986","journal-title":"Pathology"},{"key":"10.1157\/13072569_bib32","unstructured":"McGovern VJ, Shaw HM, Milton GW, Farago GA. Lymphocytic infiltration and survival in malignant melanoma. En: Ackerman AB, editor. Pathology of malignant melanoma. New York; 1981. p. 341."},{"year":"1998","series-title":"Histopathologic diagnosis of melanoma","author":"Clemente","key":"10.1157\/13072569_bib33"},{"key":"10.1157\/13072569_bib34","doi-asserted-by":"crossref","first-page":"457","DOI":"10.2307\/2281868","article-title":"Nonparametric estimation from incomplete observation","volume":"53","author":"Kaplan","year":"1957","journal-title":"J Am Stat Assoc"},{"key":"10.1157\/13072569_bib35","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1111\/j.2517-6161.1972.tb00899.x","article-title":"Regression models and life tables (with discussion)","volume":"34","author":"Cox","year":"1972","journal-title":"J Stat Soc"},{"key":"10.1157\/13072569_bib36","doi-asserted-by":"crossref","first-page":"3660","DOI":"10.1200\/JCO.2004.03.074","article-title":"Prognostic factors of thin cutaneous melanoma: an analysis of the Central Malignant Melanoma Registry of the German Dermatological Society","volume":"22","author":"Leiter","year":"2004","journal-title":"J Clin Oncol"},{"key":"10.1157\/13072569_bib37","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1001\/archderm.138.5.603","article-title":"Histological characteristics of metastasizing thin melanomas. A case-control study of 43 cases","volume":"138","author":"Guitart","year":"2002","journal-title":"Arch Dermatol"},{"key":"10.1157\/13072569_bib38","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1097\/00000372-198712000-00005","article-title":"Plasma cells within the infiltrate of primary cutaneous melanoma of the skin. A confirmation of its histoprognostic value","volume":"9","author":"Mascar\u00f3","year":"1987","journal-title":"Am J Dermatopathol"},{"key":"10.1157\/13072569_bib39","series-title":"Cutaneous melanoma","first-page":"11","article-title":"Prognostic clinical and pathologic features","author":"Stadelmann","year":"1998"},{"key":"10.1157\/13072569_bib40","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1002\/(SICI)1097-0142(19990115)85:2<383::AID-CNCR16>3.0.CO;2-3","article-title":"Survival of patients with melanoma of the lower extremity decreases with distance from the trunk","volume":"85","author":"Hsueh","year":"1999","journal-title":"Cancer"}],"container-title":["Medicina Cl\u00ednica"],"original-title":[],"language":"es","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0025775305717310?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0025775305717310?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,26]],"date-time":"2024-12-26T22:27:55Z","timestamp":1735252075000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0025775305717310"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,3]]},"references-count":40,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2005,3]]}},"alternative-id":["S0025775305717310"],"URL":"https:\/\/doi.org\/10.1157\/13072569","relation":{},"ISSN":["0025-7753"],"issn-type":[{"type":"print","value":"0025-7753"}],"subject":[],"published":{"date-parts":[[2005,3]]}}}