{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,30]],"date-time":"2022-03-30T00:27:56Z","timestamp":1648600076869},"reference-count":23,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2005,4,1]],"date-time":"2005-04-01T00:00:00Z","timestamp":1112313600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Revista Cl\u00ednica Espa\u00f1ola"],"published-print":{"date-parts":[[2005,4]]},"DOI":"10.1157\/13074165","type":"journal-article","created":{"date-parts":[[2005,4,27]],"date-time":"2005-04-27T16:15:12Z","timestamp":1114618512000},"page":"175-177","source":"Crossref","is-referenced-by-count":0,"title":["Tratamiento farmacol\u00f3gico de la obesidad"],"prefix":"10.1016","volume":"205","author":[{"given":"J.L.","family":"Pereira Cunill","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Astorga Jim\u00e9nez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"Supl","key":"10.1157\/13074165_bib1","doi-asserted-by":"crossref","first-page":"495S","DOI":"10.1093\/ajcn\/55.2.495s","article-title":"Prevalence of overweight and weight gain in the United States","volume":"55","author":"Kuczmarski","year":"1992","journal-title":"Am J Clin Nutr"},{"issue":"Supl","key":"10.1157\/13074165_bib2","doi-asserted-by":"crossref","first-page":"503S","DOI":"10.1093\/ajcn\/55.2.503s","article-title":"Economic costs of obesity","volume":"55","author":"Colditz","year":"1992","journal-title":"Am J Clin Nutr"},{"key":"10.1157\/13074165_bib3","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1157\/13046926","article-title":"Prevalencia de la obesidad en Espa\u00f1a: resultados del estudio SEEDO","volume":"120","author":"Aranceta","year":"2003","journal-title":"Med Clin (Barc)"},{"key":"10.1157\/13074165_bib4","doi-asserted-by":"crossref","first-page":"4091","DOI":"10.1093\/oxfordjournals.aje.a009843","article-title":"Prospective study of intentional weight loss and mortality in overweight white men aged 40-64 years","volume":"149","author":"Williamson","year":"1999","journal-title":"Am J Epidemiol"},{"key":"10.1157\/13074165_bib5","first-page":"123","article-title":"Long-term follow of behavioral treatment for obesity. Patterns of weight regain in men and women","volume":"13","author":"Kramer","year":"1989","journal-title":"Int J Obes"},{"key":"10.1157\/13074165_bib6","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1056\/NEJM199708283370901","article-title":"Valvular heart disease associated with fenfluramine-phentermine","volume":"337","author":"Conolly","year":"1997","journal-title":"N Engl J Med"},{"key":"10.1157\/13074165_bib7","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/S0025-7753(00)71632-0","article-title":"Sociedad Espa\u00f1ola para el Estudio de la Obesidad (SEEDO)","volume":"115","year":"2000","journal-title":"Med Clin (Barc)"},{"key":"10.1157\/13074165_bib8","unstructured":"NIH, National Heart Lung and Blood Institute, North American Association for the Study of obesity 2000. The practical guide: identification, evaluation and treatment of overweight and obesity in adults. Bethesda: NIH; NIH publication 00-4084."},{"key":"10.1157\/13074165_bib9","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S0025-7753(02)72279-3","article-title":"Estudio de la funci\u00f3n valvular en pacientes obesos tratados con sibutramina","volume":"118","author":"Pereira","year":"2002","journal-title":"Med Clin (Barc)"},{"key":"10.1157\/13074165_bib10","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1038\/sj.ijo.0800540","article-title":"Efficacy and tolerability of sibutramine in obese patients: a dose-ranging study","volume":"22","author":"Hanotin","year":"1998","journal-title":"Int J Obesity"},{"key":"10.1157\/13074165_bib11","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1002\/j.1550-8528.1999.tb00701.x","article-title":"Sibutramine produces dose-related weight loss","volume":"7","author":"Bray","year":"1999","journal-title":"Obesity Res"},{"key":"10.1157\/13074165_bib12","doi-asserted-by":"crossref","first-page":"2616","DOI":"10.1210\/jc.2004-0341","article-title":"Pharmacological Approaches to weight reduction: therapeutics targets","volume":"89","author":"Corner","year":"2004","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1157\/13074165_bib13","first-page":"69","article-title":"Tratamiento farmacol\u00f3gico en la reducci\u00f3n del exceso de grasa corporal y comorbilidades asociadas","volume":"1","author":"Garc\u00eda-Luna","year":"2004","journal-title":"Rev Esp Obes"},{"key":"10.1157\/13074165_bib14","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1592\/phco.20.4.270.34882","article-title":"Orlistat a new lipase inhibitor for the management of obesity","volume":"20","author":"Heck","year":"2000","journal-title":"Pharmacotherapy"},{"key":"10.1157\/13074165_bib15","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1038\/sj.ijo.0802475","article-title":"Long-term pharmacotherapy for overweight and obesity: a systematic review and meta-analysis of randomized controlled trial","volume":"27","author":"Padwal","year":"2003","journal-title":"Int J Obesity"},{"issue":"Supl 1","key":"10.1157\/13074165_bib16","first-page":"10S","article-title":"Clinical trial using bupropion SR with a moderate-intensity lifestyle intervention","volume":"8","author":"Anderson","year":"2000","journal-title":"Obes Res"},{"key":"10.1157\/13074165_bib17","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1056\/NEJMoa012512","article-title":"Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin","volume":"346","author":"Knowler","year":"2002","journal-title":"N Engl J Med"},{"key":"10.1157\/13074165_bib18","first-page":"109","article-title":"Effects of recombinant human leptin treatment as an adjunct of moderate energy restriction on body weight, resting energy expenditure and energy intake in obese humans","volume":"16","author":"Fogteloo","year":"2003","journal-title":"Diabetes Nutr Metab"},{"key":"10.1157\/13074165_bib19","doi-asserted-by":"crossref","first-page":"1714","DOI":"10.2337\/diabetes.50.8.1714","article-title":"A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans","volume":"50","author":"Cummings","year":"2001","journal-title":"Diabetes"},{"key":"10.1157\/13074165_bib20","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1126\/science.299.5608.849","article-title":"Obesity drug pipeline not so fat","volume":"299","author":"Gura","year":"2003","journal-title":"Science"},{"key":"10.1157\/13074165_bib21","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/S0165-6147(03)00031-2","article-title":"GIP or not GIP? That is the question","volume":"24","author":"Kieffer","year":"2003","journal-title":"Trends in Pharmacological Sciences"},{"key":"10.1157\/13074165_bib22","doi-asserted-by":"crossref","first-page":"3989","DOI":"10.1210\/jc.2003-030630","article-title":"Pancreatic polypeptide reduces appetite and food intake in humans","volume":"88","author":"Batterham","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1157\/13074165_bib23","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1056\/NEJMoa030204","article-title":"Inhibition of food intake in obese subjects by peptide YY3-36","volume":"349","author":"Batterham","year":"2003","journal-title":"N Engl J Med"}],"container-title":["Revista Cl\u00ednica Espa\u00f1ola"],"original-title":[],"language":"es","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014256505725212?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014256505725212?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,2,15]],"date-time":"2019-02-15T19:07:59Z","timestamp":1550257679000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014256505725212"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,4]]},"references-count":23,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2005,4]]}},"alternative-id":["S0014256505725212"],"URL":"https:\/\/doi.org\/10.1157\/13074165","relation":{},"ISSN":["0014-2565"],"issn-type":[{"value":"0014-2565","type":"print"}],"subject":[],"published":{"date-parts":[[2005,4]]}}}