{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,1,5]],"date-time":"2025-01-05T05:05:19Z","timestamp":1736053519707,"version":"3.32.0"},"reference-count":33,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2005,7,1]],"date-time":"2005-07-01T00:00:00Z","timestamp":1120176000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Enfermedades Infecciosas y Microbiolog\u00eda Cl\u00ednica"],"published-print":{"date-parts":[[2005,7]]},"DOI":"10.1157\/13078803","type":"journal-article","created":{"date-parts":[[2005,9,14]],"date-time":"2005-09-14T09:38:44Z","timestamp":1126690724000},"page":"438-448","source":"Crossref","is-referenced-by-count":3,"title":["S\u00edndrome respiratorio agudo grave, gripe aviar e infecci\u00f3n por metapneumovirus humano"],"prefix":"10.1016","volume":"23","author":[{"given":"Inmaculada","family":"Casas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco","family":"Pozo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1157\/13078803_bib1","doi-asserted-by":"crossref","first-page":"1967","DOI":"10.1056\/NEJMoa030747","article-title":"Identification of a novel coronavirus in patients with severe acute respiratory syndrome","volume":"348","author":"Drosten","year":"2003","journal-title":"N Engl J Med"},{"key":"10.1157\/13078803_bib2","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1126\/science.1085952","article-title":"Characterization of a novel coronavirus associated with severe acute respiratory syndrome","volume":"300","author":"Rota","year":"2003","journal-title":"Science"},{"key":"10.1157\/13078803_bib3","doi-asserted-by":"crossref","first-page":"1953","DOI":"10.1056\/NEJMoa030781","article-title":"A novel coronavirus associated with severe acute respiratory syndrome","volume":"348","author":"Ksiazek","year":"2003","journal-title":"N Engl J Med"},{"key":"10.1157\/13078803_bib4","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1128\/JVI.79.2.884-895.2005","article-title":"Characterization and complete genome sequence of a novel coronavirus, coronavirus HKU1, from patients with pneumonia","volume":"79","author":"Woo","year":"2005","journal-title":"J Virol"},{"key":"10.1157\/13078803_bib5","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/S0140-6736(03)15259-2","article-title":"Molecular epidemiology of the novel coronavirus that causes severe acute respiratory syndrome","volume":"363","author":"Guan","year":"2004","journal-title":"Lancet"},{"key":"10.1157\/13078803_bib6","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1126\/science.1087139","article-title":"Isolation and characterization of viruses related to the SRAG coronavirus from animals in southern China","volume":"302","author":"Guan","year":"2003","journal-title":"Science"},{"key":"10.1157\/13078803_bib7","doi-asserted-by":"crossref","first-page":"1779","DOI":"10.1016\/S0140-6736(03)13414-9","article-title":"Comparative fulllength genome sequence analysis of 14 SRAG coronavirus isolates and common mutations associated with putative origins of infection","volume":"361","author":"Ruan","year":"2003","journal-title":"Lancet"},{"key":"10.1157\/13078803_bib8","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1038\/nature02104","article-title":"The role of evolution in the emergence of infectious diseases","volume":"426","author":"Antia","year":"2003","journal-title":"Nature"},{"key":"10.1157\/13078803_bib9","doi-asserted-by":"crossref","first-page":"2620","DOI":"10.1128\/JVI.79.4.2620-2625.2005","article-title":"Civets are equally susceptible to experimental infection by two different severe acute respiratory syndrome coronavirus isolates","volume":"79","author":"Wu","year":"2005","journal-title":"J Virol"},{"issue":"361","key":"10.1157\/13078803_bib10","doi-asserted-by":"crossref","first-page":"1761","DOI":"10.1016\/S0140-6736(03)13410-1","article-title":"Epidemiological determinants of spread of causal agent of severe acute respiratory syndrome in Hong Kong","volume":"24","author":"Donnelly","year":"2003","journal-title":"Lancet"},{"key":"10.1157\/13078803_bib11","doi-asserted-by":"crossref","first-page":"2801","DOI":"10.1001\/jama.289.21.JOC30885","article-title":"Clinical features and short-term outcomes of 144 patients with SRAG in the greater Toronto area","volume":"289","author":"Booth","year":"2003","journal-title":"JAMA"},{"key":"10.1157\/13078803_bib12","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1111\/j.1572-0241.2005.40377.x","article-title":"Severe acute respiratory syndrome associated coronavirus is detected in intestinal tissues of fatal cases","volume":"100","author":"Shi","year":"2005","journal-title":"Am J Gastroenterol"},{"key":"10.1157\/13078803_bib13","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1097\/01.inf.0000145701.94607.28","article-title":"Severe acute respiratory syndrome can be mild in children","volume":"23","author":"Kwan","year":"2004","journal-title":"Pediatr Infect Dis J"},{"key":"10.1157\/13078803_bib14","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1002\/jmv.20096","article-title":"Evaluation of antibody responses against SRAG coronaviral nucleocapsid or spike proteins by immunoblotting or ELISA","volume":"73","author":"Huang","year":"2004","journal-title":"J Med Virol"},{"key":"10.1157\/13078803_bib15","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1056\/NEJMoa044021","article-title":"Probable person-to-person transmission of avian influen za A (H5N1)","volume":"352","author":"Ungchusak","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1157\/13078803_bib16","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1086\/315137","article-title":"Antibody response in individuals infected with avian influenza A (H5N1) viruses and detection of anti-H5 antibody among household and social contacts","volume":"180","author":"Katz","year":"1999","journal-title":"J Infect Dis"},{"key":"10.1157\/13078803_bib17","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1086\/315213","article-title":"Risk of influenza A (H5N1) infection among health care workers exposed to patients with influenza A (H5N1), Hong Kong","volume":"181","author":"Buxton Bridges","year":"2000","journal-title":"J Infect Dis"},{"key":"10.1157\/13078803_bib18","doi-asserted-by":"crossref","first-page":"2189","DOI":"10.3201\/eid1012.040759","article-title":"Avian influenza H5N1 in tigers and leopards","volume":"10","author":"Keawcharoen","year":"2004","journal-title":"Emerg Infect Dis"},{"key":"10.1157\/13078803_bib19","unstructured":"World Health Organization, Avian influenza: H5N1 detected in pigs in C.hina., 20 August 2004 Disponible en: http:\/\/www.who.int\/csr\/don\/2004_08_20\/en\/"},{"key":"10.1157\/13078803_bib20","doi-asserted-by":"crossref","first-page":"10452","DOI":"10.1073\/pnas.0403212101","article-title":"The evolution of H5N1 influenza viruses in ducks in southern China","volume":"101","author":"Chen","year":"2004","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1157\/13078803_bib21","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1126\/science.1102287","article-title":"Avian H5N1 influenza in cats","volume":"306","author":"Kuiken","year":"2004","journal-title":"Science"},{"key":"10.1157\/13078803_bib22","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1006\/viro.1999.9716","article-title":"Role of hemagglutinin cleavage for the pathogenicity of influenza virus","volume":"258","author":"Steinhauer","year":"1999","journal-title":"Virology"},{"key":"10.1157\/13078803_bib23","doi-asserted-by":"crossref","first-page":"3296","DOI":"10.1128\/JVI.63.8.3296-3300.1989","article-title":"Interplay between carbohydrate in the stalk and the length of the onnecting peptide determines the cleavability of influenza virus hemagglutinin","volume":"63","author":"Kawaoka","year":"1989","journal-title":"J Virol"},{"issue":"Suppl 2","key":"10.1157\/13078803_bib24","doi-asserted-by":"crossref","first-page":"S58","DOI":"10.1086\/338820","article-title":"Outbreak of avian influenza A(H5N1) virus infection in Hong Kong in 1997","volume":"34","author":"Chan","year":"2002","journal-title":"Clin Infect Dis"},{"key":"10.1157\/13078803_bib25","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1056\/NEJMoa040419","article-title":"World Health Organization International Avian Influenza Investigative Team. Avian influenza A (H5N1) in 10 patients in Vietnam","volume":"350","author":"Tran","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1157\/13078803_bib26","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.3201\/eid1007.040415","article-title":"Atypical avian influenza (H5N1)","volume":"10","author":"Apisarnthanarak","year":"2004","journal-title":"Emerg Infect Dis"},{"key":"10.1157\/13078803_bib27","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1056\/NEJMoa044307","article-title":"Fatal avian influenza A (H5N1) in a child presenting with diarrhea followed by coma","volume":"352","author":"De Jong","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1157\/13078803_bib28","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1292\/jvms.66.303","article-title":"Antigenic differences between H5N1 human influenza viruses isolated in 1997 and 2003","volume":"66","author":"Horimoto","year":"2004","journal-title":"J Vet Med Sci"},{"key":"10.1157\/13078803_bib29","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1038\/89098","article-title":"A newly discovered human pneumovirus isolated from young children with respiratory tract disease","volume":"7","author":"Van den Hoogen","year":"2001","journal-title":"Nat Med"},{"key":"10.1157\/13078803_bib30","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1086\/426457","article-title":"Dual infection of infants by human metapneumovirus and human respiratory syncytial virus is strongly associated with severe bronchiolitis","volume":"191","author":"Semple","year":"2005","journal-title":"J Infect Dis"},{"key":"10.1157\/13078803_bib31","doi-asserted-by":"crossref","first-page":"3631","DOI":"10.1128\/JCM.41.8.3631-3635.2003","article-title":"Comparative evaluation of real-time PCR assays for detection of the human metapneumovirus","volume":"41","author":"Cote","year":"2003","journal-title":"J Clin Microbiol"},{"key":"10.1157\/13078803_bib32","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1128\/CDLI.12.2.249-253.2005","article-title":"Development and validation of an enzyme-linked immunosorbent assay for human metapneumovirus serology based on a recombinant viral protein","volume":"12","author":"Hamelin","year":"2005","journal-title":"Clin Diagn Lab Immunol"},{"key":"10.1157\/13078803_bib33","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1016\/j.vaccine.2004.10.009","article-title":"A hostrange restricted parainfluenza virus type 3 (PIV3) expressing the human metapneumovirus (hMPV) fusion protein elicits protective immunity in African green monkeys","volume":"23","author":"Tang","year":"2005","journal-title":"Vaccine"}],"container-title":["Enfermedades Infecciosas y Microbiolog\u00eda Cl\u00ednica"],"original-title":[],"language":"es","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0213005X05749958?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0213005X05749958?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,4]],"date-time":"2025-01-04T04:20:23Z","timestamp":1735964423000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0213005X05749958"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,7]]},"references-count":33,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2005,7]]}},"alternative-id":["S0213005X05749958"],"URL":"https:\/\/doi.org\/10.1157\/13078803","relation":{},"ISSN":["0213-005X"],"issn-type":[{"type":"print","value":"0213-005X"}],"subject":[],"published":{"date-parts":[[2005,7]]}}}