{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T03:44:35Z","timestamp":1792640675967,"version":"4.5.0"},"reference-count":26,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2007,5,1]],"date-time":"2007-05-01T00:00:00Z","timestamp":1177977600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Enfermedades Infecciosas y Microbiolog\u00eda Cl\u00ednica"],"published-print":{"date-parts":[[2007,5]]},"DOI":"10.1157\/13102264","type":"journal-article","created":{"date-parts":[[2007,5,31]],"date-time":"2007-05-31T13:35:55Z","timestamp":1180618555000},"page":"300-304","source":"Crossref","is-referenced-by-count":21,"title":["Pauta corta de isoniazida y rifampicina comparada con isoniazida para la infecci\u00f3n latente de tuberculosis. Ensayo cl\u00ednico aleatorizado"],"prefix":"10.1016","volume":"25","author":[{"given":"Mar\u00eda","family":"Paloma Geijo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"Rosa Herranz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Va\u00f1o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c1ngel","family":"Jes\u00fas Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Montserrat","family":"Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9","family":"Francisco Dimas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1157\/13102264_bib1","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1157\/13048573","article-title":"Las m\u00faltiples caras del control de la tuberculosis","volume":"21","author":"Moreno","year":"2003","journal-title":"Enferm Infecc Microbiol Clin"},{"key":"10.1157\/13102264_bib2","doi-asserted-by":"crossref","first-page":"1850","DOI":"10.1056\/NEJMsa021099","article-title":"Global drug-resistance patterns and the management of latent tuberculosis infection in immigrants to the United States","volume":"347","author":"KHan","year":"2002","journal-title":"N Engl J Med"},{"key":"10.1157\/13102264_bib3","first-page":"223","article-title":"Antituberculous chemoprophylaxis with isoniazid-rifampin","volume":"39","author":"McNicol","year":"1984","journal-title":"Thorax"},{"key":"10.1157\/13102264_bib4","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1164\/ajrccm\/145.1.36","article-title":"Double-blind placebo-controlled clinical trial of three antituberculosis chemoprophylaxis regimens in patients with silicosis in Hong Kong","volume":"145","author":"Girling","year":"1992","journal-title":"Am Rev Respir Dis"},{"key":"10.1157\/13102264_bib5","doi-asserted-by":"crossref","unstructured":"British Thoracic Society Chemotherapy and management of tuberculosis in the United Kingdom: recommendations of the Joint Tuberculosis Committee of the British Thoracic Society. Thorax. 1990;45:403-8.","DOI":"10.1136\/thx.45.5.403"},{"key":"10.1157\/13102264_bib6","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1016\/S0025-7753(00)71354-6","article-title":"Incidencia de la tuberculosis en Espa\u00f1a: Resultados del Proyecto Multic\u00e9ntrico de Investigaci\u00f3n en Tuberculosis (PMIT)","volume":"114","year":"2000","journal-title":"Med Clin (Barc)"},{"issue":"Suppl RR-8","key":"10.1157\/13102264_bib7","first-page":"9","article-title":"The use of preventive therapy for tuberculosis infection in the United States","volume":"39","year":"1990","journal-title":"Recommendations of the Advisory Committee for Elimination of Tuberculosis MMWR"},{"key":"10.1157\/13102264_bib8","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1157\/13089668","article-title":"Factors associated with latent tuberculous infection in immigrants less than 35 years old","volume":"24","author":"Bran","year":"2006","journal-title":"Enferm Infecc Microbiol Clin"},{"key":"10.1157\/13102264_bib9","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/S0300-2896(02)75259-9","article-title":"Normativa sobre la prevenci\u00f3n de la tuberculosis","volume":"38","year":"2002","journal-title":"Arch Bronconeumol"},{"key":"10.1157\/13102264_bib10","unstructured":"Aguado JM, Rufi G, Garc\u00eda Rodr\u00edguez JA, Solera J. Protocolos cl\u00ednicos SEIMC. Tuberculosis. Profilaxis de Tuberculosis. Edici\u00f3n electr\u00f3nica. Octubre 2003; 14-33. Disponible en: http:\/\/www.seimc.org\/protocolos\/clinicos\/index.htm"},{"issue":"RR-6","key":"10.1157\/13102264_bib11","first-page":"1","article-title":"Targeted tuberculin testing and treatment of latent tuberculosis infection","volume":"49","year":"2000","journal-title":"MMWR"},{"key":"10.1157\/13102264_bib12","first-page":"7359","article-title":"Update: adverse event data and revised American Thoracic Society\/CDC recommendations against the use of rifampin and pyrazinamide for treatment of latent tuberculosis infectionUnited States, 2003","volume":"52","year":"2003","journal-title":"MMWR. Morb Mortal Wkly Rep"},{"key":"10.1157\/13102264_bib13","first-page":"925","article-title":"Evaluation of a tuberculosis screening program for high-risk student in Toronto schools","volume":"153","author":"Yuan","year":"1995","journal-title":"Can Med Assoc J"},{"key":"10.1157\/13102264_bib14","first-page":"401","article-title":"Cumplimentaci\u00f3n, tolerancia y eficacia de una pauta corta de quimioprofilaxis para el tratamiento de la tuberculosis","volume":"111","author":"Mart\u00ednez Alfaro","year":"1998","journal-title":"Med Clin (Barc)"},{"key":"10.1157\/13102264_bib15","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1157\/13048576","article-title":"Tratamiento directamente observado de la infecci\u00f3n tuberculosa latente: estudio comparativo de dos pautas con isoniazida","volume":"21","author":"Portilla","year":"2003","journal-title":"Enferm Infecc Microbiol Clin"},{"key":"10.1157\/13102264_bib16","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1378\/chest.99.2.465","article-title":"Toxic hepatitis with isoniacid and rifampin. A meta-analysis","volume":"99","author":"Malcolm","year":"1991","journal-title":"Chest"},{"key":"10.1157\/13102264_bib17","doi-asserted-by":"crossref","first-page":"640","DOI":"10.7326\/0003-4819-137-8-200210150-00007","article-title":"Short-Course Rifampin and Pyrazinamide Compared with Isoniazid for Latent Tuberculosis Infection: A Multicenter Clinical Trial","volume":"137","author":"Jasmer","year":"2002","journal-title":"Ann Intern Med"},{"key":"10.1157\/13102264_bib18","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1001\/jama.283.11.1445","volume":"283","author":"Gordin","year":"2000","journal-title":"JAMA"},{"key":"10.1157\/13102264_bib19","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1157\/13048575","article-title":"Ensayo cl\u00ednico aleatorizado de tres pautas de quimioprofilaxis para prevenir la tuberculosis en pacientes infectados por el VIH con anergia cut\u00e1nea","volume":"21","author":"Rivero","year":"2003","journal-title":"Enf Infec Microbiol Clin"},{"key":"10.1157\/13102264_bib20","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S0025-7753(00)71496-5","article-title":"Evaluaci\u00f3n de dos pautas de quimioprofilaxis tuberculosa en pacientes infectados por el VIH","volume":"115","author":"Mart\u00ednez Alfaro","year":"2000","journal-title":"Med Clin (Barc)"},{"key":"10.1157\/13102264_bib21","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1093\/clinids\/24.6.1264","article-title":"Asymptomatic hepatitis in persons who received alternative preventive therapy with pyrazinamide and ofloxacin","volume":"24","author":"Ridzon","year":"1997","journal-title":"Clin Infect Dis"},{"key":"10.1157\/13102264_bib22","first-page":"59","article-title":"Riesgo-beneficio del tratamiento de tuberculosis, en un hospital provincial con una sensibilidad alta de la baciloscopia","volume":"16","author":"Geijo","year":"1999","journal-title":"An Med Intern"},{"key":"10.1157\/13102264_bib23","first-page":"13","article-title":"Adherence to anti-tuberculosis chemoprophylaxis and treatment in children","volume":"10","author":"Van Zyl","year":"2006","journal-title":"Int J Tuberc Lung Dis"},{"key":"10.1157\/13102264_bib24","first-page":"186","article-title":"Estudio comparativo de isoniazida frente a una pauta corta de rifampicina y pirazinamida para el tratamiento de la infecci\u00f3n tuberculosa latente","volume":"4","author":"Tortajada","year":"2002","journal-title":"Enf Emerg"},{"key":"10.1157\/13102264_bib25","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1111\/j.1399-3062.2005.00103.x","article-title":"Prospective randomized control trial of isoniazid chemoprophylaxis during renal replacement therapy","volume":"7","author":"Vikrant","year":"2005","journal-title":"Transpl Infect Dis"},{"key":"10.1157\/13102264_bib26","doi-asserted-by":"crossref","first-page":"2719","DOI":"10.1001\/jama.293.22.2719","article-title":"Effect of routine isoniazid preventive therapy on tuberculosis incidence among HIV-infected men in South Africa: a novel randomized incremental recruitment study","volume":"293","author":"Grant","year":"2005","journal-title":"JAMA"}],"container-title":["Enfermedades Infecciosas y Microbiolog\u00eda Cl\u00ednica"],"original-title":[],"language":"es","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0213005X07742908?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0213005X07742908?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,28]],"date-time":"2019-04-28T10:59:06Z","timestamp":1556449146000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0213005X07742908"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,5]]},"references-count":26,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2007,5]]}},"alternative-id":["S0213005X07742908"],"URL":"https:\/\/doi.org\/10.1157\/13102264","relation":{},"ISSN":["0213-005X"],"issn-type":[{"value":"0213-005X","type":"print"}],"subject":[],"published":{"date-parts":[[2007,5]]}}}