{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T20:21:20Z","timestamp":1769631680475,"version":"3.49.0"},"reference-count":14,"publisher":"American Association for Cancer Research (AACR)","issue":"1","content-domain":{"domain":["aacrjournals.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,1,13]]},"abstract":"<jats:title>Summary:<\/jats:title>\n               <jats:p>As we cannot reliably distinguish indolent, low-risk ductal carcinoma in situ (DCIS) from potentially progressive, high-risk DCIS, all women with DCIS diagnosis undergo intensive treatment without any benefit. The PREvent ductal Carcinoma In Situ Invasive Overtreatment Now team was established to unravel DCIS biology and develop new multidisciplinary approaches for accurate risk stratification to tackle the global problem of DCIS overdiagnosis and overtreatment.<\/jats:p>\n               <jats:p>See related article by Bressan et al., p. 16<\/jats:p>\n               <jats:p>See related article by Stratton et al., p. 22<\/jats:p>\n               <jats:p>See related article by Goodwin et al., p. 34<\/jats:p>","DOI":"10.1158\/2159-8290.cd-24-1201","type":"journal-article","created":{"date-parts":[[2025,1,13]],"date-time":"2025-01-13T08:10:46Z","timestamp":1736755846000},"page":"28-33","update-policy":"https:\/\/doi.org\/10.1158\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Conquering Overtreatment of DCIS: Lessons from PRECISION"],"prefix":"10.1158","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7108-063X","authenticated-orcid":false,"given":"Proteeti","family":"Bhattacharjee","sequence":"first","affiliation":[{"name":"1Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam, the Netherlands."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3488-4935","authenticated-orcid":false,"given":"Esther H.","family":"Lips","sequence":"additional","affiliation":[{"name":"1Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam, the Netherlands."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8285-4111","authenticated-orcid":false,"given":"Elinor J.","family":"Sawyer","sequence":"additional","affiliation":[{"name":"2School of Cancer and Pharmaceutical Sciences, Faculty of Life Sciences and Medicine, Guy\u2019s Cancer Centre, King\u2019s College London, London, United Kingdom."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8571-1148","authenticated-orcid":false,"given":"E. 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