{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T07:18:33Z","timestamp":1788247113064,"version":"build-2803163510"},"reference-count":9,"publisher":"American Association for Cancer Research (AACR)","issue":"9","content-domain":{"domain":["aacrjournals.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,9,1]]},"abstract":"<jats:title>Summary:<\/jats:title>\n                  <jats:p>We provide an overview of a recent study in Cancer Discovery by Leongamornlert and colleagues involving genomic profiling of 30 patients with myeloproliferative neoplasms using available blood or bone marrow samples to assess what factors underlie disease evolution or predict stability.<\/jats:p>\n                  <jats:p>See related article by Leongamornlert et al., p. 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Harvard, Cambridge, Massachusetts."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0044-443X","authenticated-orcid":false,"given":"Vijay G.","family":"Sankaran","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00dvg7y05","id-type":"ROR","asserted-by":"publisher"}],"name":"Boston Children\u2019s Hospital 1 Division of Hematology\/Oncology, , Harvard Medical School, Boston, Massachusetts."},{"name":"2Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts."},{"name":"3Howard Hughes Medical Institute, Boston, Massachusetts."},{"name":"4Broad Institute of MIT and Harvard, Cambridge, Massachusetts."},{"name":"5Harvard Stem Cell Institute, Cambridge, Massachusetts."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1086","published-online":{"date-parts":[[2026,9,1]]},"reference":[{"key":"2026090103074056800_bib1","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1016\/j.hoc.2020.12.001","article-title":"Overview of myeloproliferative neoplasms: history, pathogenesis, diagnostic criteria, and complications","volume":"35","author":"Tremblay","year":"2022","journal-title":"Hematol Oncol Clin North Am"},{"key":"2026090103074056800_bib2","doi-asserted-by":"publisher","first-page":"1416","DOI":"10.1056\/nejmoa1716614","article-title":"Classification and personalized prognosis in myeloproliferative neoplasms","volume":"379","author":"Grinfeld","year":"2018","journal-title":"N Engl J Med"},{"key":"2026090103074056800_bib3","doi-asserted-by":"publisher","first-page":"1843","DOI":"10.1158\/2159-8290.CD-26-0410","article-title":"Genomic evolution and natural history of myeloproliferative neoplasms on 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