{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T00:37:29Z","timestamp":1792370249708,"version":"4.4.0"},"reference-count":0,"publisher":"American Association for Cancer Research (AACR)","issue":"9","content-domain":{"domain":["aacrjournals.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,9,1]]},"abstract":"<jats:title>Abstract:<\/jats:title>\n                  <jats:p>China has approved the first CAR T-cell therapy that targets solid tumors, satricabtagene autoleucel (satri-cel), for patients with claudin 18.2\u2013positive, HER2-negative gastric or gastro-esophageal junction cancer. The approval stems from a phase II trial that found the cells increased progression-free survival and overall survival. Scientists are excited about the decision but caution that more research is necessary to improve the effectiveness of CAR T cells against solid tumors.<\/jats:p>","DOI":"10.1158\/2159-8290.cd-nw2026-0078","type":"journal-article","created":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T09:45:56Z","timestamp":1784627156000},"page":"OF1-OF1","update-policy":"https:\/\/doi.org\/10.1158\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["First CAR T-Cell Therapy Approved for Solid Tumors"],"prefix":"10.1158","volume":"16","member":"1086","published-online":{"date-parts":[[2026,7,21]]},"container-title":["Cancer Discovery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aacrjournals.org\/cancerdiscovery\/article\/doi\/10.1158\/2159-8290.CD-NW2026-0078\/786956\/First-CAR-T-Cell-Therapy-Approved-for-Solid","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/aacrjournals.org\/cancerdiscovery\/article\/16\/9\/OF1\/787672\/First-CAR-T-Cell-Therapy-Approved-for-Solid","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/aacrjournals.org\/cancerdiscovery\/article\/16\/9\/OF1\/787672\/First-CAR-T-Cell-Therapy-Approved-for-Solid","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T07:09:46Z","timestamp":1788246586000},"score":1,"resource":{"primary":{"URL":"https:\/\/aacrjournals.org\/cancerdiscovery\/article\/16\/9\/OF1\/787672\/First-CAR-T-Cell-Therapy-Approved-for-Solid"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,21]]},"references-count":0,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2026,7,21]]},"published-print":{"date-parts":[[2026,9,1]]}},"URL":"https:\/\/doi.org\/10.1158\/2159-8290.cd-nw2026-0078","relation":{},"ISSN":["2159-8274","2159-8290"],"issn-type":[{"value":"2159-8274","type":"print"},{"value":"2159-8290","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,21]]}}}