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Their study shows that the key genetic hallmarks of disease are largely restricted to the plasma-cell compartment and raises caution that assays detecting minimal residual disease may yield false-positive results by detecting rare clonotypic B cells.<\/jats:p>\n                  <jats:p>See related article by Gonzalez et al., p. 558<\/jats:p>","DOI":"10.1158\/2643-3230.bcd-26-0109","type":"journal-article","created":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T12:31:41Z","timestamp":1779366701000},"page":"503-505","update-policy":"https:\/\/doi.org\/10.1158\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["New Insights into the Role of Clonotypic B Cells in Plasma-cell 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