{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"institution":[{"name":"American Association for Cancer Research"}],"indexed":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T13:25:32Z","timestamp":1764163532098,"version":"3.46.0"},"posted":{"date-parts":[[2023,7,5]]},"reference-count":0,"publisher":"American Association for Cancer Research (AACR)","license":[{"start":{"date-parts":[[2023,7,5]],"date-time":"2023-07-05T00:00:00Z","timestamp":1688515200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>&lt;div&gt;AbstractBackground:&lt;p&gt;The Canadian Cancer Registry (CCR) does not collect demographic data beyond age and sex, making it difficult to monitor health inequalities. Using data linkage, we compared site-specific cancer incidence rates by race.&lt;\/p&gt;Methods:&lt;p&gt;The 2006 and 2011 Canadian Census Health and Environment Cohorts are population-based probabilistically linked datasets of 5.9 million respondents of the 2006 long-form census and 6.5 million respondents of the 2011 National Household Survey. Race was self-reported. Respondent data were linked with the CCR up to 2015. We calculated age-standardized incidence rate ratios (ASIRR), comparing group-specific rates to the overall population rate with bootstrapped 95% confidence intervals (CI). We used negative binomial regressions to adjust for socioeconomic variables and assess interactions with immigration status.&lt;\/p&gt;Results:&lt;p&gt;The age-standardized overall cancer incidence rate was lower in almost all non-White racial groups than in the overall population, except for White and Indigenous peoples who had higher incidence rates than the overall population (ASIRRs, 1.03\u20131.04). Immigrants had substantially lower age-standardized overall cancer incidence rates than nonimmigrants (ASIRR, 0.83; 95% CI, 0.82\u20130.84). Stomach, liver, and thyroid cancers and multiple myelomas were the sites where non-White racial groups had consistently higher site-specific cancer incidence rates than the overall population. Immigration status was an important modifier of cancer risk in the interaction model.&lt;\/p&gt;Conclusions:&lt;p&gt;Differences in cancer incidence between racial groups are likely influenced by differences in lifestyles, early life exposures, and selection factors for immigration.&lt;\/p&gt;Impact:&lt;p&gt;Data linkage can help monitor health inequalities and assess progress in preventive interventions against cancer.&lt;\/p&gt;&lt;p&gt;&lt;i&gt;&lt;a href=\"https:\/\/aacrjournals.org\/cebp\/article\/doi\/10.1158\/1055-9965.EPI-23-0326\" target=\"_blank\"&gt;See related commentary by Withrow and Gomez, p. 876&lt;\/a&gt;&lt;\/i&gt;&lt;\/p&gt;&lt;\/div&gt;<\/jats:p>","DOI":"10.1158\/1055-9965.c.6727174","type":"posted-content","created":{"date-parts":[[2023,7,5]],"date-time":"2023-07-05T06:52:56Z","timestamp":1688539976000},"source":"Crossref","is-referenced-by-count":0,"title":["Data from Site-Specific Cancer Incidence by Race and Immigration Status in Canada 2006\u20132015: A Population-Based Data Linkage Study"],"prefix":"10.1158","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9505-3564","authenticated-orcid":false,"given":"Tal\u00eda","family":"Malag\u00f3n","sequence":"first","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5808-0179","authenticated-orcid":false,"given":"Samantha","family":"Morais","sequence":"first","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7903-1413","authenticated-orcid":false,"given":"Parker","family":"Tope","sequence":"first","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5190-0370","authenticated-orcid":false,"given":"Mariam","family":"El-Zein","sequence":"first","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4409-8084","authenticated-orcid":false,"given":"Eduardo L.","family":"Franco","sequence":"first","affiliation":[]}],"member":"1086","container-title":[],"original-title":[],"deposited":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T13:22:23Z","timestamp":1764163343000},"score":1,"resource":{"primary":{"URL":"https:\/\/aacr.figshare.com\/collections\/Data_from_Site-Specific_Cancer_Incidence_by_Race_and_Immigration_Status_in_Canada_2006_2015_A_Population-Based_Data_Linkage_Study\/6727174\/1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,5]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1158\/1055-9965.c.6727174","relation":{"is-preprint-of":[{"id-type":"doi","id":"10.1158\/1055-9965.EPI-22-1191","asserted-by":"subject"}]},"subject":[],"published":{"date-parts":[[2023,7,5]]},"subtype":"other"}}