{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T12:28:47Z","timestamp":1789993727690,"version":"4.0.1"},"reference-count":3,"publisher":"S. Karger AG","issue":"5","license":[{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Caries Res"],"published-print":{"date-parts":[[2000]]},"abstract":"<jats:p>The aims of this study were to assess whether multiple salivary mutans streptococcal (ms) counts have a higher predictive power than a single one, and whether the predictive power of the test is different at different levels of fluoride exposure, oral hygiene and sucrose consumption. Three salivary ms tests were performed at 3\u2013month intervals (positive test: salivary ms \u22655\u00d710&lt;sup&gt;5&lt;\/sup&gt; cfu\/ ml) on a sample of 304, initially caries\u2013free, 6\u2013 to 7\u2013year\u2013olds. Plaque index was also assessed and the parents filled out a questionnaire concerning sucrose\u2013containing eating events and fluoride exposure. Sensitivity, specificity and Youden's index (J) were used to compare the predictive power. Thirty\u2013six percent of the children developed caries during the 2\u2013year follow\u2013up. The highest J value for a single ms test (the second) was 0.24 (sensitivity 29.1%, specificity 95.4%). The multiple ms test with the highest J value (0.29) was obtained by the dichotomies 0 vs. 1\u20133 positive tests (sensitivity 50.0%, specificity 79.9%) and 0\u20131 vs. 2\u20133 positive tests (sensitivity 31.8%, specificity 97.4%). The predictive power of the multiple test was passable for children with low fluoride exposure and high plaque index (sensitivity 57.4%, specificity 93.7%, J 0.51), while it was low for the other groups. Sucrose exposure did not significantly affect the predictive power of the ms test.sion.<\/jats:p>","DOI":"10.1159\/000016612","type":"journal-article","created":{"date-parts":[[2003,4,15]],"date-time":"2003-04-15T17:25:18Z","timestamp":1050427518000},"page":"380-387","source":"Crossref","is-referenced-by-count":16,"title":["Caries Prediction by Multiple Salivary Mutans Streptococcal Counts in Caries\u2013Free Children with Different Levels of Fluoride Exposure, Oral Hygiene and Sucrose Intake"],"prefix":"10.1159","volume":"34","author":[{"given":"S.","family":"Petti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.W.","family":"Hausen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2000,9,7]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1080\/000163598422956"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9969(73)90109-X"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1080\/000163598422893"}],"container-title":["Caries Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/16612","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/16612","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:45:09Z","timestamp":1745469909000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000016612"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000]]},"references-count":3,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2000,10,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000016612","archive":["Portico"],"relation":{},"ISSN":["0008-6568","1421-976X"],"issn-type":[{"value":"0008-6568","type":"print"},{"value":"1421-976X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000]]}}}