{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T23:14:19Z","timestamp":1775862859400,"version":"3.50.1"},"reference-count":6,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[1999,1,1]],"date-time":"1999-01-01T00:00:00Z","timestamp":915148800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[1999,1,1]],"date-time":"1999-01-01T00:00:00Z","timestamp":915148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatology"],"published-print":{"date-parts":[[1999]]},"abstract":"<jats:p>&lt;b&gt;Background:&lt;\/b&gt; In autoimmune bullous skin diseases, accumulation of neutrophils and\/or eosinophils in the affected skin represents a characteristic feature. So far, however, the induction of this granulocyte infiltration has not been elucidated. &lt;b&gt;Objective:&lt;\/b&gt; Regarding their biological effects, the chemokines interleukin 8 (IL-8) and RANTES (regulated upon activation normal T lymphocyte expressed and secreted) could play a role in this granulocyte accumulation. &lt;b&gt;Methods:&lt;\/b&gt; Immunohistochemical examination of lesional skin from patients with bullous pemphigoid, pemphigus, dermatitis herpetiformis and linear IgA disease was performed using a set of different antibodies against IL-8 and RANTES. Additionally, blister fluids were screened for soluble RANTES peptide using an ELISA. &lt;b&gt;Results:&lt;\/b&gt; No difference in chemokine expression was found in lesions of autoimmune bullous diseases compared to normal skin. &lt;b&gt;Conclusion:&lt;\/b&gt; In contrast to chronic inflammatory diseases like psoriasis and eczema, where keratinocyte IL-8 immunoreactivity was found to differ from normal skin, keratinocyte immunoreactivity is not altered in autoimmune bullous diseases.<\/jats:p>","DOI":"10.1159\/000018085","type":"journal-article","created":{"date-parts":[[2003,4,15]],"date-time":"2003-04-15T17:25:18Z","timestamp":1050427518000},"page":"118-121","source":"Crossref","is-referenced-by-count":11,"title":["Lack of Expression of Interleukin 8 and RANTES in Autoimmune Bullous Skin Diseases"],"prefix":"10.1159","volume":"198","author":[{"given":"E.","family":"Bornscheuer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Zillikens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.-M.","family":"Schr\u00f6der","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Sticherling","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[1999,4,26]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.132.3.315"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/0952-7915(94)90006-X"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/1043-4666(91)90013-4"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1084\/jem.176.2.587"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12495817"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1084\/jem.176.6.1489"}],"container-title":["Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/18085","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/18085","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:55:03Z","timestamp":1745470503000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000018085"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999]]},"references-count":6,"journal-issue":{"issue":"2","published-online":{"date-parts":[[1999,7,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000018085","archive":["Portico"],"relation":{},"ISSN":["1018-8665","1421-9832"],"issn-type":[{"value":"1018-8665","type":"print"},{"value":"1421-9832","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999]]}}}