{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T00:32:50Z","timestamp":1780446770914,"version":"3.54.1"},"reference-count":3,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatology"],"published-print":{"date-parts":[[2000]]},"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; Pityriasis rubra pilaris (PRP) is reported to respond poorly to cyclosporin A (CsA). &lt;i&gt;Objective:&lt;\/i&gt; We attempted to determine the efficacy of CsA in the treatment of classic adult-type PRP. &lt;i&gt;Methods:&lt;\/i&gt; Three patients with classic adult-type PRP were treated with 5\u00a0mg\/kg\/day CsA. &lt;i&gt;Results:&lt;\/i&gt; A sustained clinical response was achieved within 2\u20134 weeks of therapy. Relapses were noted when the CsA dose was decreased to 1.2\u00a0mg\/kg\/day. &lt;i&gt;Conclusion:&lt;\/i&gt; CsA should be considered in the treatment of classical adult-type PRP.<\/jats:p>","DOI":"10.1159\/000018397","type":"journal-article","created":{"date-parts":[[2003,4,15]],"date-time":"2003-04-15T17:25:18Z","timestamp":1050427518000},"page":"324-327","source":"Crossref","is-referenced-by-count":31,"title":["Three Cases of Pityriasis rubra pilaris Successfully Treated with Cyclosporin A"],"prefix":"10.1159","volume":"200","author":[{"given":"Kazunari","family":"Usuki","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitsuhiro","family":"Sekiyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tokihiko","family":"Shimada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shoko","family":"Shimada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamotsu","family":"Kanzaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2000,7,6]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1080\/000155500750012153"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.126.3.339"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.129.10.1346"}],"container-title":["Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/18397","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/18397","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:59:07Z","timestamp":1745470747000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000018397"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000]]},"references-count":3,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2000,7,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000018397","archive":["Portico"],"relation":{},"ISSN":["1018-8665","1421-9832"],"issn-type":[{"value":"1018-8665","type":"print"},{"value":"1421-9832","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000]]}}}