{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T14:47:54Z","timestamp":1788187674454,"version":"build-2803163510"},"reference-count":0,"publisher":"S. Karger AG","issue":"6","license":[{"start":{"date-parts":[[1999,1,1]],"date-time":"1999-01-01T00:00:00Z","timestamp":915148800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[1999,1,1]],"date-time":"1999-01-01T00:00:00Z","timestamp":915148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ophthalmologica"],"published-print":{"date-parts":[[1999]]},"abstract":"<jats:p>&lt;i&gt;Purpose:&lt;\/i&gt; To evaluate the conjunctival structure and inflammatory cell counts and to determine the predictive value of these histological parameters for postoperative intraocular pressure (IOP) levels after trabeculectomy. &lt;i&gt;Methods:&lt;\/i&gt; A clinical and histological study was performed on consecutive patients. Postoperative (mean 32.8 \u00b1 18.4 months; range 6\u201360 months) conjunctival biopsies of 36 eyes of 28 primary open-angle glaucoma patients who had trabeculectomy between 1992 and 1995 were included in the study. According to postoperative pressure control, patients with \u226416 mm Hg and those with &gt;16\u00a0mm Hg were taken as groups\u00a01 and 2, respectively. The control group (group\u00a03) consisted of 15 age-matched patients without glaucoma, who had received no topical therapy. We compared the conjunctival structure and cell counts within these groups. Goblet cells, acute inflammatory cells, chronic inflammatory cells, fibroblasts, epithelial thickness, vascular density, mucopolysaccharides and collagen compositions were determined in groups\u00a01, 2 and 3. &lt;i&gt;Results:&lt;\/i&gt; The number of goblet cells was significantly higher in group\u00a01 (6.74 \u00b1 7.23) than group\u00a02 (3.09 \u00b1 2.77; p = 0.017). No statistical difference was observed in the number of acute inflammatory cells, chronic inflammatory cells, fibroblasts, epithelial thickness, vascular density, mucopolysaccharide or collagen compositions between groups\u00a01 and 2 (p &gt; 0.05). In addition, when groups\u00a01 and 2 were compared with the control group, there was a significant decrease in goblet cells (p &lt; 0.001), an increase in acute inflammatory cells, chronic inflammatory cells, fibroblasts, epithelial thickness and vascular density (p &lt; 0.001), but there was no significant difference in mucopolysaccharide and collagen compositions (p &gt; 0.05). &lt;i&gt;Conclusions:&lt;\/i&gt; This study suggests that at the time of surgery a high number of goblet cells may be a predictor of lowered IOP (\u226416\u00a0mm Hg) following trabeculectomy without antimetabolite.<\/jats:p>","DOI":"10.1159\/000027457","type":"journal-article","created":{"date-parts":[[2003,4,15]],"date-time":"2003-04-15T09:24:25Z","timestamp":1050398665000},"page":"371-375","source":"Crossref","is-referenced-by-count":14,"title":["Effect of Conjunctival Structure and Inflammatory Cell Counts on Intraocular Pressure after Trabeculectomy"],"prefix":"10.1159","volume":"213","author":[{"given":"Mustafa Kemal","family":"Ar\u0131c\u0131","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00fcleyman","family":"Demircan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ay\u015fen","family":"Topalkara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cenap","family":"G\u00fcler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Handan","family":"Aker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dilek Sema","family":"Ar\u0131c\u0131","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[1999,11,2]]},"container-title":["Ophthalmologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/27457","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/27457","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:06:27Z","timestamp":1745467587000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000027457"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999]]},"references-count":0,"journal-issue":{"issue":"6","published-online":{"date-parts":[[1999,12,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000027457","archive":["Portico"],"relation":{},"ISSN":["0030-3755","1423-0267"],"issn-type":[{"value":"0030-3755","type":"print"},{"value":"1423-0267","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999]]}}}