{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T04:12:38Z","timestamp":1745554358838,"version":"3.40.4"},"reference-count":13,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pharmacology"],"published-print":{"date-parts":[[2000]]},"abstract":"<jats:p>We examined the effects of repeated exposure to forced walking stress for 6 h once a day for 0, 6 and 9 consecutive days on formalin-induced paw licking in mice. In each observation period, stress-induced antinociception (SIA) was observed only in the late phase (from 10 to 30\u00a0min), but not in the early phase (from 0 to 10 min) of formalin-induced paw licking in mice. Moreover, it was hard to develop tolerance even by daily exposure to stress for 6 days, although SIA for 9 days decreased compared with those for 0 and 6 days. Naloxone (10 mg\/kg), an opioid-receptor antagonist, was effective in reducing the SIA induced by forced walking stress for 6 days and\/or 9 days, but not for 0 days. Furthermore, the experiments with selective opioid-receptor antagonists, \u03b2-funaltrexamine (\u03bc) naltrindol (\u03b4), or nor-binaltorphimine (\u03ba) demonstrated that SIA induced by forced walking stress for 9 successive days may be mediated through opioid \u03b4- and \u03ba-receptors. Finally, although SIA seemed to be a unitary phenomenon, the present results strengthened the idea that SIA is induced by exposure to forced walking stress with characteristics dependent on the duration of exposure.<\/jats:p>","DOI":"10.1159\/000028387","type":"journal-article","created":{"date-parts":[[2003,4,15]],"date-time":"2003-04-15T13:07:10Z","timestamp":1050412030000},"page":"96-100","source":"Crossref","is-referenced-by-count":7,"title":["Differential Involvement of Opioid Receptors in Stress-Induced Antinociception Caused by Repeated Exposure to Forced Walking Stress in Mice"],"prefix":"10.1159","volume":"61","author":[{"given":"Kenji","family":"Onodera","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinobu","family":"Sakurada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seiichi","family":"Furuta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akihiko","family":"Yonezawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kinue","family":"Arai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takafumi","family":"Hayashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sou","family":"Katsuyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takumi","family":"Sato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuichi","family":"Miyazaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kensuke","family":"Kisara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2000,8,14]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/0149-7634(80)90025-1"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1037\/\/0735-7044.102.2.233"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(86)91472-1"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/0024-3205(85)90492-8"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1254\/jjp.79.83"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/0165-0270(85)90116-5"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3959(90)91167-H"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(83)90777-1"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.pharmtox.25.1.193"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.pharmtox.32.1.239"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1038\/5706"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(86)91046-2"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/0028-3908(88)90124-4"}],"container-title":["Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/28387","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/28387","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:15:58Z","timestamp":1745468158000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000028387"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000]]},"references-count":13,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2000,8,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000028387","archive":["Portico"],"relation":{},"ISSN":["0031-7012","1423-0313"],"issn-type":[{"type":"print","value":"0031-7012"},{"type":"electronic","value":"1423-0313"}],"subject":[],"published":{"date-parts":[[2000]]}}}