{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T15:53:08Z","timestamp":1791474788711,"version":"4.3.4"},"reference-count":3,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2002,1,1]],"date-time":"2002-01-01T00:00:00Z","timestamp":1009843200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2002,1,1]],"date-time":"2002-01-01T00:00:00Z","timestamp":1009843200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Blood Purif"],"published-print":{"date-parts":[[2002]]},"abstract":"<i>Background\/Aim:<\/i> The measurement of the vascular access blood flow rate (Q<sub>a<\/sub>) in chronic hemodialyzed patients was proposed to predict access thrombosis. We have recently presented a new method based on the measurements of ionic dialysance at normal and reversed positions of the blood lines. We evaluate the reliability of the measurement of Q<sub>a<\/sub> by this method in detecting significant access stenoses. <i>Methods:<\/i> Twenty-five patients on chronic hemodialysis and having a vascular access cannulated with two needles were studied. The Q<sub>a<\/sub> was evaluated by the Diascan<sup>\u00ae<\/sup> ionic dialysance (Q<sub>a-id<\/sub>) method and by the ultrasound dilution technique (Q<sub>a-us<\/sub>; Transonic<sup>\u00ae<\/sup>) during the same dialysis session. The measurements were available for 23 patients. In addition, the patients had ultrasonography of their fistula followed by angiography, if a stenosis was detected. <i>Results:<\/i> Q<sub>a-id<\/sub> and Q<sub>a-us<\/sub> were not significantly different, showing a difference in Q<sub>a<\/sub> at 32 \u00b1 469 ml\/min. Q<sub>a-id<\/sub> was significantly different between patients with or without stenosis (508 \u00b1 241 vs. 1,125 \u00b1 652 ml\/min, p < 0.05). Among patients with a Q<sub>a<\/sub> <500 ml\/min by Q<sub>a-id<\/sub>, 5 had a stenosis detected by ultrasonography (sensitivity 83%), and 3 had no stenosis (false-positive rate 18%). Of these 3 patients, 2 had a thrombotic event at 1 and 3 months, suggesting that a more sensitive detection of stenosis for this range of Q<sub>a<\/sub> is needed and that a Q<sub>a<\/sub> <500 ml\/min has a higher power to predict thromboses than a stenosis by ultrasonography. <i>Conclusions:<\/i> The measurement of the access flow rate by the Q<sub>a-id<\/sub> method has a clinical relevance to the detection of vascular access stenosis. An intervention program based on the Q<sub>a-id<\/sub> has to be evaluated.<\/jats:p>","DOI":"10.1159\/000047006","type":"journal-article","created":{"date-parts":[[2003,4,15]],"date-time":"2003-04-15T12:11:24Z","timestamp":1050408684000},"page":"177-181","source":"Crossref","is-referenced-by-count":15,"title":["Detection of Vascular Access Stenosis by Measurement of Access Blood Flow from Ionic Dialysance"],"prefix":"10.1159","volume":"20","author":[{"given":"Lucile","family":"Mercadal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuel","family":"Challier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Cluzel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdelaziz","family":"Hamani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hac\u00e8ne","family":"Boulechfar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhora","family":"Boukhalfa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hassane","family":"Izzedine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nader","family":"Bassilios","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beno\u00eet","family":"Barrou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilbert","family":"Deray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thierry","family":"Petitclerc","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2002,1,30]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.1998.00158.x"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.1998.00145.x"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2000.00344.x"}],"container-title":["Blood Purification"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/47006","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/47006","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T03:48:08Z","timestamp":1745466488000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000047006"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002]]},"references-count":3,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2002,7,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000047006","archive":["Portico"],"relation":{},"ISSN":["0253-5068","1421-9735"],"issn-type":[{"value":"0253-5068","type":"print"},{"value":"1421-9735","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002]]}}}