{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T23:37:25Z","timestamp":1792107445415,"version":"4.4.0"},"reference-count":2,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2001,1,1]],"date-time":"2001-01-01T00:00:00Z","timestamp":978307200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2001,1,1]],"date-time":"2001-01-01T00:00:00Z","timestamp":978307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Caries Res"],"published-print":{"date-parts":[[2001]]},"abstract":"<jats:p>The purpose was to discover whether fluoride (F) accumulates in the aged human pineal gland. The aims were to determine (a) F\u2013concentrations of the pineal gland (wet), corresponding muscle (wet) and bone (ash); (b) calcium\u2013concentration of the pineal. Pineal, muscle and bone were dissected from 11 aged cadavers and assayed for F using the HMDS\u2013facilitated diffusion, F\u2013ion\u2013specific electrode method. Pineal calcium was determined using atomic absorption spectroscopy. Pineal and muscle contained 297\u00b1257 and 0.5\u00b10.4 mg F\/kg wet weight, respectively; bone contained 2,037\u00b11,095 mg F\/kg ash weight. The pineal contained 16,000\u00b111,070 mg Ca\/kg wet weight. There was a positive correlation between pineal F and pineal Ca (r = 0.73, p&lt;0.02) but no correlation between pineal F and bone F. By old age, the pineal gland has readily accumulated F and its F\/Ca ratio is higher than bone.<\/jats:p>","DOI":"10.1159\/000047443","type":"journal-article","created":{"date-parts":[[2003,4,15]],"date-time":"2003-04-15T12:11:24Z","timestamp":1050408684000},"page":"125-128","source":"Crossref","is-referenced-by-count":50,"title":["Fluoride Deposition in the Aged Human Pineal Gland"],"prefix":"10.1159","volume":"35","author":[{"given":"J.","family":"Luke","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2001,3,9]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/0162-0134(93)80006-U"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(87)90720-7"}],"container-title":["Caries Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/47443","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/47443","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T03:53:03Z","timestamp":1745466783000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000047443"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001]]},"references-count":2,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2001,4,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000047443","archive":["Portico"],"relation":{},"ISSN":["0008-6568","1421-976X"],"issn-type":[{"value":"0008-6568","type":"print"},{"value":"1421-976X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001]]}}}