{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T04:11:16Z","timestamp":1745554276135,"version":"3.40.4"},"reference-count":1,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2001,1,1]],"date-time":"2001-01-01T00:00:00Z","timestamp":978307200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2001,1,1]],"date-time":"2001-01-01T00:00:00Z","timestamp":978307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Caries Res"],"published-print":{"date-parts":[[2001]]},"abstract":"<jats:p>The effect of calcium (Ca) concentrations and added ethanol on fluoride (F) depositions by experimental two\u2013component rinses, each consisting of a Ca\u2013containing and an F\u2013containing component, was evaluated in an in vitro system. Among the tested rinses, a 3 mmol\/l F two\u2013component rinse with 200 mmol\/l Ca and 10% v\/v ethanol was found to produce the greatest F deposition relative to the F concentration in the rinse. Specifically, this rinse produced an F deposition that was about 7 times greater than a conventional 13.2\u2013mmol\/l sodium fluoride (NaF) rinse. In a second experiment, an in vitro pH cycling model was used to evaluate the potential anti\u2013caries effects of 4 rinses: (1) placebo rinse (no F), (2) 13.2\u2013mmol\/l NaF rinse, (3) 52.6\u2013mmol\/l NaF rinse, and (4) the 3\u2013mmol\/l F two\u2013component rinse in a 7\u2013day in vitro pH cycling model. The changes in lesion mineral contents, delta(\u0394Z), as assessed by quantitative microradiographic measurements, were as follows [mean \u00b1 standard deviation, n = 10]: (1) 72.5\u00b110.2 \u00b5m, (2) 43.4\u00b15.6 \u00b5m, (3) 17.3\u00b110.2 \u00b5m and (4) 45.3\u00b15.2 \u00b5m. These results showed that the 3\u2013mmol\/l F two\u2013component rinse produced the same (p&gt;0.05) protection against demineralization as did the 13.2\u2013mmol\/l NaF rinse which had 4 times the fluoride content. The results suggest that it is possible to formulate an effective low\u2013F two\u2013component rinse.<\/jats:p>","DOI":"10.1159\/000047460","type":"journal-article","created":{"date-parts":[[2003,4,15]],"date-time":"2003-04-15T12:11:24Z","timestamp":1050408684000},"page":"223-228","source":"Crossref","is-referenced-by-count":12,"title":["Effect of a Low\u2013Fluoride\u2013Content, Two\u2013Component Rinse on Fluoride Uptake and on De\u2013 and Remineralization of Enamel Lesions: An in vitro Study"],"prefix":"10.1159","volume":"35","author":[{"given":"S.","family":"Takagi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Liao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.C.","family":"Chow","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2001,5,24]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/0167-7322(93)80030-Y"}],"container-title":["Caries Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/47460","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/47460","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T03:53:12Z","timestamp":1745466792000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000047460"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001]]},"references-count":1,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2001,6,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000047460","archive":["Portico"],"relation":{},"ISSN":["0008-6568","1421-976X"],"issn-type":[{"type":"print","value":"0008-6568"},{"type":"electronic","value":"1421-976X"}],"subject":[],"published":{"date-parts":[[2001]]}}}