{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T06:55:30Z","timestamp":1761893730047,"version":"3.40.4"},"reference-count":0,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2002,1,1]],"date-time":"2002-01-01T00:00:00Z","timestamp":1009843200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2002,1,1]],"date-time":"2002-01-01T00:00:00Z","timestamp":1009843200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ophthalmologica"],"published-print":{"date-parts":[[2002]]},"abstract":"<jats:p>&lt;i&gt;Purpose:&lt;\/i&gt; To compare central corneal swelling after 24 h in eyes wearing Lotrafilcon A (high Dk silicone hydrogel) and Vifilcon A (low Dk hydrogel) lenses and the fellow control eyes of rabbits. &lt;i&gt;Methods:&lt;\/i&gt; 24 New Zealand albino rabbits, free of corneal and conjunctival disease, were anaesthetised with ketamine and xylazin. In 12 rabbits, the right eye was fit with the high Dk Lotrafilcon A silicone hydrogel lens. In the other 12 rabbits, the right eye was fit with the low Dk Vifilcon A hydrogel lens, whereas the left eyes were kept as control eyes. Thereafter, the lens-fitted eyes had partial tarsorrhaphy that left a central gap of approximately 4 mm in length. After 24 h the eyelids were opened and the lenses removed. Central corneal thickness was measured using an ultrasonic pachymeter (Mentor O&amp;#38;O-Advent). &lt;i&gt;Results:&lt;\/i&gt; Central corneal oedema induced by Vifilcon A lens was significantly higher than that with the Lotrafilcon A lens (p &lt; 0.0001). The oedema of the fellow eyes paired with the Vifilcon A lens-wearing eyes was also higher than that of the fellow eyes paired with the Lotrafilcon A lens-wearing eyes (p &lt; 0.01). &lt;i&gt;Conclusions:&lt;\/i&gt; The Lotrafilcon A lens induced significantly less corneal oedema than the Vifilcon A lens. Corneal oedema of the fellow eyes appears to be influenced by the swelling of the contralateral lens-wearing eyes. The oedema of the fellow control eye was significantly lower when there was less oedema in the contralateral eye wearing a high Dk silicone hydrogel lens. This may be a sympathetic physiological response. The presence of silicone in the high Dk hydrogel lens may suppress corneal oedema in the lens-wearing eye, thus affecting the fellow eye.<\/jats:p>","DOI":"10.1159\/000048314","type":"journal-article","created":{"date-parts":[[2003,4,15]],"date-time":"2003-04-15T13:07:10Z","timestamp":1050412030000},"page":"139-143","source":"Crossref","is-referenced-by-count":8,"title":["Oedematous Corneal Response of the Fellow Control Eye to Lotrafilcon A and Vifilcon A Hydrogel Contact Lenses in the Rabbit"],"prefix":"10.1159","volume":"216","author":[{"given":"Mustafa","family":"Guzey","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmet","family":"Satici","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adil","family":"Kilic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sezin","family":"Karadede","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2002,4,2]]},"container-title":["Ophthalmologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/48314","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/48314","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:02:19Z","timestamp":1745467339000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000048314"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2002,4,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000048314","archive":["Portico"],"relation":{},"ISSN":["0030-3755","1423-0267"],"issn-type":[{"type":"print","value":"0030-3755"},{"type":"electronic","value":"1423-0267"}],"subject":[],"published":{"date-parts":[[2002]]}}}