{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:51:26Z","timestamp":1787017886941,"version":"build-2736575974"},"reference-count":2,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2002,1,1]],"date-time":"2002-01-01T00:00:00Z","timestamp":1009843200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2002,1,1]],"date-time":"2002-01-01T00:00:00Z","timestamp":1009843200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Respiration"],"published-print":{"date-parts":[[2002]]},"abstract":"<jats:p>We present an extremely rare case of hemophagocytic syndrome (HPS) induced by fulminant &lt;i&gt;Mycoplasma pneumoniae&lt;\/i&gt;&lt;i&gt;(Mp)&lt;\/i&gt; pneumonia in an elderly adult. Erythrocytopenia and thrombocytopenia were observed in a patient with acute respiratory failure, liver dysfunction and renal failure. &lt;i&gt;Mp&lt;\/i&gt;-associated HPS was diagnosed in this case by clinical and laboratory findings, including a bone marrow aspiration specimen and serum &lt;i&gt;Mp&lt;\/i&gt; antibody titer. High serum levels of soluble interleukin-2 receptor, interleukin-6, human interleukin-10 and macrophage-colony stimulating factor were observed. Hypercytokinemia is a useful marker of disease activity and prognosis. Combined treatment with methylprednisolone and erythromycin was successful and led to a favorable outcome. Physicians should be aware of HPS as a complication in &lt;i&gt;Mp&lt;\/i&gt; infection.<\/jats:p>","DOI":"10.1159\/000049377","type":"journal-article","created":{"date-parts":[[2003,4,15]],"date-time":"2003-04-15T06:10:37Z","timestamp":1050387037000},"page":"87-91","source":"Crossref","is-referenced-by-count":18,"title":["An Elderly Patient with Hemophagocytic Syndrome due to Severe &lt;i&gt;Mycoplasma&lt;\/i&gt; Pneumonia with Marked Hypercytokinemia"],"prefix":"10.1159","volume":"69","author":[{"given":"Ryusuke","family":"Mizukane","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun-ichi","family":"Kadota","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiyuki","family":"Yamaguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takakazu","family":"Kiya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiromichi","family":"Fukushima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masao","family":"Nakatomi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shigeru","family":"Kohno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2002,2,8]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1097\/00043426-199907000-00011"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1159\/000029280"}],"container-title":["Respiration"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/49377","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/49377","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T00:14:46Z","timestamp":1745453686000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000049377"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002]]},"references-count":2,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2002,2,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000049377","archive":["Portico"],"relation":{},"ISSN":["0025-7931","1423-0356"],"issn-type":[{"value":"0025-7931","type":"print"},{"value":"1423-0356","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002]]}}}