{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T04:11:56Z","timestamp":1745554316698,"version":"3.40.4"},"reference-count":2,"publisher":"S. Karger AG","issue":"Suppl. 2","license":[{"start":{"date-parts":[[1998,1,1]],"date-time":"1998-01-01T00:00:00Z","timestamp":883612800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[1998,1,1]],"date-time":"1998-01-01T00:00:00Z","timestamp":883612800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Digestion"],"published-print":{"date-parts":[[1998]]},"abstract":"<jats:p>Hemorrhage from ruptured gastroesophageal varices is the main complication of portal hypertension, and represents a major cause of death and of liver transplantation in patients with cirrhosis [1]. Variceal bleeding is the last step of a chain which is initiated by the increase in portal pressure, followed by the formation and progressive dilatation of the varices until these finally rupture and bleed. Approximately 10% of patients having varices will develop variceal hemorrhage per year [2].<\/jats:p>","DOI":"10.1159\/000051410","type":"journal-article","created":{"date-parts":[[2003,4,15]],"date-time":"2003-04-15T12:11:24Z","timestamp":1050408684000},"page":"2-5","source":"Crossref","is-referenced-by-count":2,"title":["Pathogenesis of Bleeding in Portal Hypertension"],"prefix":"10.1159","volume":"59","author":[{"given":"Angels","family":"Escorsell","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaume","family":"Bosch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[1998,8,17]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1080\/003655201750313432"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(95)91740-3"}],"container-title":["Digestion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/51410","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/51410","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:05:29Z","timestamp":1745467529000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000051410"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998]]},"references-count":2,"journal-issue":{"issue":"Suppl. 2","published-online":{"date-parts":[[1998,7,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000051410","archive":["Portico"],"relation":{},"ISSN":["0012-2823","1421-9867"],"issn-type":[{"type":"print","value":"0012-2823"},{"type":"electronic","value":"1421-9867"}],"subject":[],"published":{"date-parts":[[1998]]}}}