{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T04:12:17Z","timestamp":1745554337989,"version":"3.40.4"},"reference-count":2,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2001,1,1]],"date-time":"2001-01-01T00:00:00Z","timestamp":978307200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2001,1,1]],"date-time":"2001-01-01T00:00:00Z","timestamp":978307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Digestion"],"published-print":{"date-parts":[[2001]]},"abstract":"<i>Aims:<\/i> To explore the patterns of gastric electrical activity, gastric emptying and gastrointestinal hormones in dyspeptic patients and relate them to <i>Helicobacter pylori<\/i> status. <i>Methods:<\/i> Twenty-two patients with functional dyspepsia and 29 healthy volunteers underwent cutaneous electrogastrography and dynamic ultrasound before and after a test meal. All dyspeptic patients underwent endoscopy and biopsy; all subjects were examined for the presence of antibodies to <i>H. pylori, <\/i>and the plasma levels of gastrin, neurotensin, cholecystokinin, and pancreatic polypeptide were measured. <i>Results:<\/i> The area under the curve (AUC) of the normal slow wave percentage was lower in dyspeptic patients than controls (Kruskal-Wallis p = 0.016; Dunn\u2019s test: <i>H. pylori-<\/i>positive patients: 21,235.5 [19,101.0\u201322,688.8] vs. <i>H. pylori-<\/i>negative controls: 22,532.0 [20,133.0\u201323,755.0], p < 0.05). The AUC of the tachygastria percentage was higher in dyspeptic patients than controls (p = 0.0001; <i>H. pylori-<\/i>positive patients: 2,173.5 [325.8\u20133,055.3] vs. <i>H. pylori-<\/i>negative controls: 682.0 [118.5\u20131,902.4], p < 0.05; <i>H. pylori-<\/i>negative patients: 1,843.0 [1,107.0\u20134,277.0] vs. <i>H. pylori-<\/i>negative controls: 682.0 [118.5\u20131,902.4], p < 0.05). The AUC of gastrin was higher in <i>H. pylori-<\/i>positive than <i>H. pylori-<\/i>negative subjects (p = 0.0002; <i>H. pylori-<\/i>positive patients: 16,146.5 [11,368.8\u201333,141.7] vs. <i>H. pylori-<\/i>negative controls: 11,250.0 [5,674.0\u201317,448.0], p < 0.05; <i>H. pylori-<\/i>positive controls: 20,250.0 [12,070.0\u201364,430.0] vs. <i>H. pylori-<\/i>negative controls: 11,250.0 [5,674.0\u201317,448.0], p < 0.05). In the total group of dyspeptic patients and in the <i>H. pylori-<\/i>positive patients, a negative correlation was found between the AUC of neurotensin and the total score for postprandial fullness (dyspeptic patients r = \u20130.51, p = 0.01; <i>H. pylori-<\/i>positive patients r = \u20130.66, p = 0.02). <i>Conclusions:<\/i> In dyspeptic patients, alterations in gastric electrical activity were not related to <i>H. pylori <\/i>infection. Nevertheless, <i>H. pylori<\/i> infection induces higher gastrin levels in both patients and asymptomatic subjects.<\/jats:p>","DOI":"10.1159\/000051868","type":"journal-article","created":{"date-parts":[[2003,4,15]],"date-time":"2003-04-15T13:07:10Z","timestamp":1050412030000},"page":"20-29","source":"Crossref","is-referenced-by-count":13,"title":["Gastric Electrical Activity and Gastrointestinal Hormones in Dyspeptic Patients"],"prefix":"10.1159","volume":"63","author":[{"given":"Giuseppe","family":"Riezzo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marisa","family":"Chiloiro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Russo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caterina","family":"Clemente","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni","family":"Di Matteo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vito","family":"Guerra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfredo","family":"Di Leo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2001,1,15]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1097\/00005176-199810000-00014"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1097\/00004836-199706000-00006"}],"container-title":["Digestion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/51868","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/51868","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:10:46Z","timestamp":1745467846000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000051868"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001]]},"references-count":2,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2001,7,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000051868","archive":["Portico"],"relation":{},"ISSN":["0012-2823","1421-9867"],"issn-type":[{"type":"print","value":"0012-2823"},{"type":"electronic","value":"1421-9867"}],"subject":[],"published":{"date-parts":[[2001]]}}}