{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T15:47:48Z","timestamp":1761580068594,"version":"3.40.4"},"reference-count":4,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2002,1,1]],"date-time":"2002-01-01T00:00:00Z","timestamp":1009843200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2002,1,1]],"date-time":"2002-01-01T00:00:00Z","timestamp":1009843200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pharmacology"],"published-print":{"date-parts":[[2002]]},"abstract":"<jats:p>In urethane-anesthetized rats, we examined the effect of bilateral superior cervical ganglionectomy on interleukin-1\u03b2 (IL-1\u03b2)-induced elevation of plasma catecholamines. In sham-operated rats, intracerebroventricularly (i.c.v.) administered IL-1\u03b2 (100 ng\/animal) effectively elevated plasma noradrenaline rather than plasma adrenaline. In superior cervical ganglionectomized rats, however, IL-1\u03b2 significantly elevated adrenaline to a greater extent than noradrenaline, and they were attenuated by i.c.v. administration of melatonin (100 ng\/animal). Superior cervical ganglionectomy effectively reduced the plasma level of melatonin and urinary excretion of 6-sulfatoxymelatonin (a main urinary melatonin metabolite). These results suggest that superior cervical ganglia inhibit central sympatho-adrenomedullary outflow (especially adrenomedullary outflow) by increasing melatonin synthesis in the pineal gland of rats.<\/jats:p>","DOI":"10.1159\/000058039","type":"journal-article","created":{"date-parts":[[2003,4,15]],"date-time":"2003-04-15T21:05:17Z","timestamp":1050440717000},"page":"136-140","source":"Crossref","is-referenced-by-count":1,"title":["Interleukin-1\u03b2-Induced Increases of Plasma Catecholamine Levels in Rats: Enhancement by Superior Cervical Ganglionectomy"],"prefix":"10.1159","volume":"65","author":[{"given":"Muchun","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshinori","family":"Murakami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shoshiro","family":"Okada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kunihiko","family":"Yokotani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2002,6,5]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1254\/jjp.81.29"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(87)90365-9"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(83)90578-4"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/0024-3205(84)90361-8"}],"container-title":["Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/58039","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/58039","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T03:58:07Z","timestamp":1745467087000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000058039"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002]]},"references-count":4,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2002,7,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000058039","archive":["Portico"],"relation":{},"ISSN":["0031-7012","1423-0313"],"issn-type":[{"type":"print","value":"0031-7012"},{"type":"electronic","value":"1423-0313"}],"subject":[],"published":{"date-parts":[[2002]]}}}