{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T10:42:40Z","timestamp":1774953760274,"version":"3.50.1"},"reference-count":2,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2002,1,1]],"date-time":"2002-01-01T00:00:00Z","timestamp":1009843200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2002,1,1]],"date-time":"2002-01-01T00:00:00Z","timestamp":1009843200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Caries Res"],"published-print":{"date-parts":[[2002]]},"abstract":"<jats:p>Representative strains of &lt;i&gt;Streptococcus mutans&lt;\/i&gt; and &lt;i&gt;Streptococcus sobrinus &lt;\/i&gt;showed differences in susceptibility to members of the monobactam group of \u03b2-lactam antibiotics: &lt;i&gt;S. sobrinus&lt;\/i&gt; was less sensitive than &lt;i&gt;S. mutans&lt;\/i&gt;. The minimum inhibitory concentrations of aztreonam (AZT) and carumonam, both of which belong to this group, were 2,000 \u00b5g\/ml for &lt;i&gt;S. sobrinus&lt;\/i&gt; and 125 \u00b5g\/ml for &lt;i&gt;S. mutans&lt;\/i&gt;. Further addition of fosfomycin, bacitracin and sodium chloride to Mitis Salivarius agar (MS) supplemented with AZT resulted in growth inhibition of &lt;i&gt;S. mutans&lt;\/i&gt; and oral streptococci other than &lt;i&gt;S. sobrinus,&lt;\/i&gt; and was therefore used as a selective medium for &lt;i&gt;S. sobrinus&lt;\/i&gt; (MS-SOB medium). The average growth recovery of laboratory and clinically isolated strains of &lt;i&gt;S. sobrinus&lt;\/i&gt; on MS-SOB medium was 74.1% compared to that on MS medium. Seventy-eight percent of clinical samples in which &lt;i&gt;S. sobrinus&lt;\/i&gt; was detected yielded pure growth of &lt;i&gt;S. sobrinus &lt;\/i&gt;on MS-SOB medium.<\/jats:p>","DOI":"10.1159\/000059329","type":"journal-article","created":{"date-parts":[[2003,4,15]],"date-time":"2003-04-15T21:05:17Z","timestamp":1050440717000},"page":"155-160","source":"Crossref","is-referenced-by-count":35,"title":["Susceptibility of &lt;i&gt;Streptococcus mutans &lt;\/i&gt;and &lt;i&gt;Streptococcus sobrinus&lt;\/i&gt; to Cell Wall Inhibitors and Development of a Novel Selective Medium for &lt;i&gt;S. sobrinus&lt;\/i&gt;"],"prefix":"10.1159","volume":"36","author":[{"given":"M.","family":"Hirasawa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Takada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2002,6,7]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1159\/000016430"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9969(73)90109-X"}],"container-title":["Caries Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/59329","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/59329","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:02:03Z","timestamp":1745467323000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000059329"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002]]},"references-count":2,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2002,6,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000059329","archive":["Portico"],"relation":{},"ISSN":["0008-6568","1421-976X"],"issn-type":[{"value":"0008-6568","type":"print"},{"value":"1421-976X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002]]}}}