{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T12:51:43Z","timestamp":1791118303355,"version":"4.1.0"},"reference-count":4,"publisher":"S. Karger AG","issue":"3-4","license":[{"start":{"date-parts":[[2002,1,1]],"date-time":"2002-01-01T00:00:00Z","timestamp":1009843200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2002,1,1]],"date-time":"2002-01-01T00:00:00Z","timestamp":1009843200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cerebrovasc Dis"],"published-print":{"date-parts":[[2002]]},"abstract":"<jats:p>&lt;i&gt;Background: &lt;\/i&gt;Subjects with stroke in a first-degree relative are at increased risk of atherothrombotic vascular disease. We aimed to examine atherothrombotic risk factors in such a population. &lt;i&gt;Methods:&lt;\/i&gt; 145 subjects with a first-degree relative with stroke and 143 controls were recruited. Measurements were made of features of the insulin resistance syndrome, haemostatic and fibrinolytic risk factors, and glucose tolerance tests. &lt;i&gt;Results:&lt;\/i&gt; The relatives had higher systolic blood pressure, HDL, 2-hour glucose, factor VII:C, fibrinogen, vWF and more had smoked. Differences remained in factor VII:C, systolic BP and 2-hour glucose after adjustment. &lt;i&gt;Conclusions:&lt;\/i&gt; This population demonstrates adverse thrombotic risk factors and increased FVII:C activity may contribute to increased cardiovascular risk.<\/jats:p>","DOI":"10.1159\/000065677","type":"journal-article","created":{"date-parts":[[2003,4,15]],"date-time":"2003-04-15T21:05:17Z","timestamp":1050440717000},"page":"153-160","source":"Crossref","is-referenced-by-count":10,"title":["Atherothrombotic Risk Factors in Subjects with a Family History of Stroke"],"prefix":"10.1159","volume":"14","author":[{"given":"Alastair J.","family":"Lansbury","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter J.","family":"Grant","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew J.","family":"Catto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2002,10,25]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/0026-0495(86)90209-X"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199503093321003"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(94)90064-7"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9150(95)05638-6"}],"container-title":["Cerebrovascular Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/65677","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/65677","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:32:34Z","timestamp":1745469154000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000065677"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002]]},"references-count":4,"journal-issue":{"issue":"3-4","published-online":{"date-parts":[[2002,10,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000065677","archive":["Portico"],"relation":{},"ISSN":["1015-9770","1421-9786"],"issn-type":[{"value":"1015-9770","type":"print"},{"value":"1421-9786","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002]]}}}