{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T04:09:07Z","timestamp":1745554147297,"version":"3.40.4"},"reference-count":6,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2002,1,1]],"date-time":"2002-01-01T00:00:00Z","timestamp":1009843200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2002,1,1]],"date-time":"2002-01-01T00:00:00Z","timestamp":1009843200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatology"],"published-print":{"date-parts":[[2002]]},"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; Extensive \u2018cauliflower-like\u2019 condyloma acuminatum (CA) in males is commonly treated with CO&lt;sub&gt;2&lt;\/sub&gt; laser surgery or with electrosurgery. Studies on the long-term outcome in this specific situation are scarce. &lt;i&gt;Objectives:&lt;\/i&gt; To determine the cure and recurrence rate in relation to the HIV status and endoanal location of lesions. To determine the complication rate and patient satisfaction. &lt;i&gt;Methods:&lt;\/i&gt; Questionnaire-based retrospective long-term study on 64 consecutive men (answer rate 60% or 64\/107 addressed persons). The mean follow-up was 25 months (range 7\u201375). &lt;i&gt;Results:&lt;\/i&gt; The overall cure rate after 1 intervention was 67%. The cure rate in HIV-positive versus HIV-negative patients was 58 versus 71% (odds ratio = 1.79; p = 0.38). Endoanal versus perianal location was associated with a cure rate of 56 versus 84% (odds ratio = 4.06; p = 0.03). After a second treatment session, the cure rate increased to 79% or higher in all subgroups. Painful defecation for an average of 4\u20135 weeks was the main postoperative complaint. Severe complications were not seen or reported. &lt;i&gt;Conclusions:&lt;\/i&gt; The CO&lt;sub&gt;2&lt;\/sub&gt; laser is a valuable and safe treatment to debulk extensive \u2018cauliflower- like\u2019 anogenital CA in males. The healing rate in HIV-positive patients is not significantly lower than in HIV-negative patients. Endoanal location of lesions is a risk factor for recurrence.<\/jats:p>","DOI":"10.1159\/000065844","type":"journal-article","created":{"date-parts":[[2003,4,15]],"date-time":"2003-04-15T21:05:40Z","timestamp":1050440740000},"page":"255-259","source":"Crossref","is-referenced-by-count":19,"title":["CO&lt;sub&gt;2&lt;\/sub&gt; Laser Surgery for Extensive, Cauliflower-Like Anogenital Condylomata acuminata: Retrospective Long-Term Study on 19 HIV-Positive and 45 HIV-Negative Men"],"prefix":"10.1159","volume":"205","author":[{"given":"Patrizia M.","family":"Carrozza","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giorgio M.","family":"Merlani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00fcnter","family":"Burg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00fcrg","family":"Hafner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2002,10,21]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1007\/s001050051254"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.134.1.33"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097\/00007435-200104000-00007"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1258\/0956462011924218"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1159\/000017906"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1159\/000051686"}],"container-title":["Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/65844","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/65844","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T03:10:02Z","timestamp":1745464202000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000065844"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002]]},"references-count":6,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2002,7,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000065844","archive":["Portico"],"relation":{},"ISSN":["1018-8665","1421-9832"],"issn-type":[{"type":"print","value":"1018-8665"},{"type":"electronic","value":"1421-9832"}],"subject":[],"published":{"date-parts":[[2002]]}}}