{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T01:16:11Z","timestamp":1767834971390,"version":"3.49.0"},"reference-count":6,"publisher":"S. Karger AG","issue":"Suppl. 1","license":[{"start":{"date-parts":[[2002,1,1]],"date-time":"2002-01-01T00:00:00Z","timestamp":1009843200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2002,1,1]],"date-time":"2002-01-01T00:00:00Z","timestamp":1009843200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gynecol Obstet Invest"],"published-print":{"date-parts":[[2002]]},"abstract":"<jats:p>This article is a review of the efficacy of medical and surgical treatment of endometriosis-associated infertility and pelvic pain. Endometriosis is the cause of pelvic pain (dysmenorrhea, dyspareunia) and infertility in more than 35% of women of reproductive age. Complete resolution of endometriosis is not yet possible but therapy has essentially three main objectives: (1) to reduce pain; (2) to increase the possibility of pregnancy; (3) to delay recurrence for as long as possible. It could be concluded that a consensus will probably never be reached on minimal and mild endometriosis. Nevertheless, because the Canadian study reported a large number of cases, we strongly support the view that visible endometriosis must be removed at the time of surgery. In cases of moderate and severe endometriosis-associated infertility, the combined approach (operative laparoscopy with GnRH-a) must be considered as \u2018first-line\u2019 treatment. The mean pregnancy rate of 50% reported in the literature following surgery provides scientific proof that operative treatment should be undertaken first to give our patients the best chance of conceiving naturally.<\/jats:p>","DOI":"10.1159\/000066288","type":"journal-article","created":{"date-parts":[[2003,4,15]],"date-time":"2003-04-15T12:11:24Z","timestamp":1050408684000},"page":"2-10","source":"Crossref","is-referenced-by-count":42,"title":["The Efficacy of Medical and Surgical Treatment of Endometriosis-Associated Infertility and Pelvic Pain"],"prefix":"10.1159","volume":"54","author":[{"given":"Jacques","family":"Donnez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean","family":"Squifflet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C\u00e9line","family":"Pirard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pascale","family":"Jadoul","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"Wyns","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mireille","family":"Smets","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2002,12,2]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1097\/00001703-200008000-00009"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(98)00166-6"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(97)00360-9"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199707243370401"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(01)03262-9"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-2115(98)00028-1"}],"container-title":["Gynecologic and Obstetric Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/66288","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/66288","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T03:14:23Z","timestamp":1745464463000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000066288"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002]]},"references-count":6,"journal-issue":{"issue":"Suppl. 1","published-online":{"date-parts":[[2002,12,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000066288","archive":["Portico"],"relation":{},"ISSN":["0378-7346","1423-002X"],"issn-type":[{"value":"0378-7346","type":"print"},{"value":"1423-002X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002]]}}}