{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T04:09:45Z","timestamp":1745554185029,"version":"3.40.4"},"reference-count":0,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2002,12,23]],"date-time":"2002-12-23T00:00:00Z","timestamp":1040601600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2002,12,23]],"date-time":"2002-12-23T00:00:00Z","timestamp":1040601600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gyn\u00e4kol Geburtshilfliche Rundsch"],"published-print":{"date-parts":[[2003]]},"abstract":"<jats:p>Als Therapie eines prim\u00e4ren Hyperparathyreoidismus (pHPT) in der Schwangerschaft wird die Parathyreoidektomie im 2. Schwangerschaftstrimenon empfohlen, da in 90% der F\u00e4lle ein Adenom der Nebenschilddr\u00fcse Ursache dieser Erkrankung ist. In dem hier beschriebenen Fall wird der Verlauf eines schweren pHPT in der Schwangerschaft dargestellt, bei dem eine operative Therapie nicht m\u00f6glich war, da die Ursache des pHPT nicht gekl\u00e4rt werden konnte. Eine 29-j\u00e4hrige Primigravida stellte sich in der 11. Schwangerschaftswoche mit pHPT unklarer Genese vor. Trotz Hyperkalzi\u00e4mie mit Werten &gt;3,05 mmol\/l (Normalbereich: 2,05\u20132,65) w\u00e4hrend der gesamten Schwangerschaft wurde die Patientin in der 35. Schwangerschaftswoche von einem eutrophen M\u00e4dchen entbunden. Bei dem Kind konnte mit fr\u00fchzeitiger Kalzium- und Vitamin-D&lt;sub&gt;3&lt;\/sub&gt;-Substitution sowie phosphatarmer Ern\u00e4hrung durch Muttermilch eine Hypokalzi\u00e4mie vermieden werden. Im weiteren Verlauf entwickelte sich das Kind altersentsprechend. Fazit: Schwerer Hyperparathyreoidismus w\u00e4hrend der gesamten Schwangerschaft f\u00fchrt nicht notwendigerweise zu einer gravierenden fetalen bzw. neonatalen Morbidit\u00e4t.<\/jats:p>","DOI":"10.1159\/000067164","type":"journal-article","created":{"date-parts":[[2003,4,15]],"date-time":"2003-04-15T21:05:40Z","timestamp":1050440740000},"page":"36-38","source":"Crossref","is-referenced-by-count":3,"title":["Prim\u00e4rer Hyperparathyreoidismus mit persistierender Hyperkalzi\u00e4mie in der Schwangerschaft"],"prefix":"10.1159","volume":"43","author":[{"given":"M.","family":"von Poblotzki","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Strauss","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Schulze","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Hepp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2002,12,23]]},"container-title":["Gyn\u00e4kologisch-geburtshilfliche Rundschau"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/67164","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/67164","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T03:22:48Z","timestamp":1745464968000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000067164"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,12,23]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2003,1,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000067164","archive":["Portico"],"relation":{},"ISSN":["1018-8843","1423-0011"],"issn-type":[{"type":"print","value":"1018-8843"},{"type":"electronic","value":"1423-0011"}],"subject":[],"published":{"date-parts":[[2002,12,23]]}}}