{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T08:35:16Z","timestamp":1792658116888,"version":"4.5.0"},"reference-count":3,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2003,1,1]],"date-time":"2003-01-01T00:00:00Z","timestamp":1041379200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2003,1,1]],"date-time":"2003-01-01T00:00:00Z","timestamp":1041379200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatology"],"published-print":{"date-parts":[[2003]]},"abstract":"<jats:p>&lt;i&gt;Background: &lt;\/i&gt;The microbiological basis of diaper dermatitis is not clearly elucidated, although a better knowledge of microbial colonisation can be of importance with regard to an adequate treatment. &lt;i&gt;Objective:&lt;\/i&gt; To investigate the relevance of &lt;i&gt;Candida &lt;\/i&gt;sp. and &lt;i&gt;Staphylococcus aureus&lt;\/i&gt; colonisation in diaper dermatitis and to determine the correlation between the extent of colonisation and the severity of disease. &lt;i&gt;Methods: &lt;\/i&gt;Growth of &lt;i&gt;Candida&lt;\/i&gt; sp. and &lt;i&gt;S. aureus&lt;\/i&gt; in the perianal, inguinal and oral regions was determined by positive\/negative and semi-quantitative analysis in an open, multi-centre (n = 3) study. Forty-eight children with healthy skin and 28 with diaper dermatitis were analysed. The severity of diaper dermatitis was assessed using a total symptoms score. &lt;i&gt;Results: &lt;\/i&gt;Colonisation by &lt;i&gt;Candida &lt;\/i&gt;sp. was significantly more frequent in children with diaper dermatitis as compared to those with healthy skin (perianal 75 vs. 19%; inguinal 50 vs. 10%; oral 68 vs. 25%, p &lt; 0.0003), whereas colonisation by &lt;i&gt;S. aureus&lt;\/i&gt; at the 3 swab locations was not different (p &gt; 0.34). There was a highly significant, positive correlation between severity of disease and extent of &lt;i&gt;Candida &lt;\/i&gt;sp. colonisation at all swab locations. &lt;i&gt;Conclusions:&lt;\/i&gt; Limited microbial colonisation in diaper dermatitis is of questionable relevance, but extensive colonisation seems to aggravate the symptoms; therefore, we suggest that semi-quantitative evaluation should be preferred to the positive\/negative assessment for a differential diagnosis.<\/jats:p>","DOI":"10.1159\/000068472","type":"journal-article","created":{"date-parts":[[2003,4,15]],"date-time":"2003-04-15T21:05:40Z","timestamp":1050440740000},"page":"136-141","source":"Crossref","is-referenced-by-count":62,"title":["Microbiological Aspects of Diaper Dermatitis"],"prefix":"10.1159","volume":"206","author":[{"given":"G.","family":"Ferrazzini","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.R.","family":"Kaiser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.-K.","family":"Hirsig Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Wehrli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Della Casa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Pohlig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Gonser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Graf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.","family":"J\u00f6rg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2003,3,10]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-199709000-00013"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-4362.1999.00757.x"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1159\/000018366"}],"container-title":["Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/68472","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/68472","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T03:34:15Z","timestamp":1745465655000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000068472"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003]]},"references-count":3,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2003,7,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000068472","archive":["Portico"],"relation":{},"ISSN":["1018-8665","1421-9832"],"issn-type":[{"value":"1018-8665","type":"print"},{"value":"1421-9832","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003]]}}}