{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T14:13:23Z","timestamp":1753884803510,"version":"3.40.4"},"reference-count":4,"publisher":"S. Karger AG","issue":"1-2","license":[{"start":{"date-parts":[[2003,1,1]],"date-time":"2003-01-01T00:00:00Z","timestamp":1041379200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2003,1,1]],"date-time":"2003-01-01T00:00:00Z","timestamp":1041379200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Digestion"],"published-print":{"date-parts":[[2003]]},"abstract":"<jats:p>Clinically significant liver disease is probably a rare condition in Turner\u2019s syndrome and only a few cases of severe liver disease have been described. The natural history of patients with Turner\u2019s syndrome and elevated cholestatic liver enzymes is unclear. We report a case with a long history of intrahepatic cholestasis and without clinical or histopathological progression in 12 years of follow-up. Like some other reports our case suggests, also histologically, that the liver disease in these patients runs a benign course.<\/jats:p>","DOI":"10.1159\/000069702","type":"journal-article","created":{"date-parts":[[2003,5,12]],"date-time":"2003-05-12T15:51:21Z","timestamp":1052754681000},"page":"96-99","source":"Crossref","is-referenced-by-count":10,"title":["Chronic Cholestasis Associated with Turner\u2019s Syndrome: 12 Years of Clinical and Histopathological Follow-Up"],"prefix":"10.1159","volume":"67","author":[{"given":"Joram","family":"Wardi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Boleslaw","family":"Knobel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Shahmurov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enrique","family":"Melamud","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yona","family":"Avni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haim","family":"Shirin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2003,5,13]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1159\/000007712"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1007\/s004310051163"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2000.8263"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199612053352307"}],"container-title":["Digestion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/dig\/article-pdf\/67\/1-2\/96\/4036071\/000069702.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/dig\/article-pdf\/67\/1-2\/96\/4036071\/000069702.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T03:46:45Z","timestamp":1745466405000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000069702"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003]]},"references-count":4,"journal-issue":{"issue":"1-2","published-online":{"date-parts":[[2003,7,1]]},"published-print":{"date-parts":[[2003,12,31]]}},"URL":"https:\/\/doi.org\/10.1159\/000069702","archive":["Portico"],"relation":{},"ISSN":["0012-2823","1421-9867"],"issn-type":[{"type":"print","value":"0012-2823"},{"type":"electronic","value":"1421-9867"}],"subject":[],"published":{"date-parts":[[2003]]}}}