{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T04:09:44Z","timestamp":1745554184265,"version":"3.40.4"},"reference-count":6,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2003,1,1]],"date-time":"2003-01-01T00:00:00Z","timestamp":1041379200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2003,1,1]],"date-time":"2003-01-01T00:00:00Z","timestamp":1041379200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Surg Res"],"published-print":{"date-parts":[[2003]]},"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; We investigated the effect of intraluminal glutamine on the intestinal mucosa in the presence of ischemia-reperfusion injury (IRI). &lt;i&gt;Methods:&lt;\/i&gt; Six blind sacs were created in the small bowel (3 at the jejunum and 3 at the ileum) in 10 Wistar rats. The lateral sacs of both bowel regions were submitted to IRI (30\/30 min), while the medial sacs were left free to receive blood supply. In the lateral sacs, a solution containing either saline plus 4% glutamine or pure saline was injected at the bowel lumen. No fluid was injected in the medial sacs. &lt;i&gt;Results:&lt;\/i&gt; Both at the jejunum and at the ileum, the score of the mucosal injury was higher in saline-injected sacs than in either glutamine-injected or control sacs. There was a significantly greater number of neutrophils in the sacs treated with saline than in the other two groups of sacs. &lt;i&gt;Conclusion:&lt;\/i&gt; Glutamine protects the mucosa and diminishes the accumulation of neutrophils at the lamina propria of the small bowel in IRI.<\/jats:p>","DOI":"10.1159\/000070606","type":"journal-article","created":{"date-parts":[[2003,6,13]],"date-time":"2003-06-13T07:08:23Z","timestamp":1055488103000},"page":"352-356","source":"Crossref","is-referenced-by-count":9,"title":["Benefits of Intraluminal Injection of Glutamine for Intestinal Mucosa during Ischemia-Reperfusion"],"prefix":"10.1159","volume":"35","author":[{"given":"J.E.","family":"de Aguilar-Nascimento","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cl\u00e1udia","family":"Gurgel Marques","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandra","family":"Carvalho Mariano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Bicudo Salom\u00e3o","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"de Souza Neves","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2003,6,17]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1006\/jsre.1994.1054"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-199904000-00005"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/0891-5849(93)90092-9"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/0009-2797(90)90085-2"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1006\/jsre.1995.1025"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-200105270-00010"}],"container-title":["European Surgical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/70606","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/70606","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T03:22:37Z","timestamp":1745464957000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000070606"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003]]},"references-count":6,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2003,8,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000070606","archive":["Portico"],"relation":{},"ISSN":["0014-312X","1421-9921"],"issn-type":[{"type":"print","value":"0014-312X"},{"type":"electronic","value":"1421-9921"}],"subject":[],"published":{"date-parts":[[2003]]}}}