{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T09:45:13Z","timestamp":1779270313141,"version":"3.51.4"},"reference-count":8,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2003,1,1]],"date-time":"2003-01-01T00:00:00Z","timestamp":1041379200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2003,1,1]],"date-time":"2003-01-01T00:00:00Z","timestamp":1041379200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Horm Res Paediatr"],"published-print":{"date-parts":[[2003]]},"abstract":"<jats:p>&lt;i&gt;Aim:&lt;\/i&gt; To evaluate the effects of estrogen substitution on the uterine development in patients with Turner syndrome. &lt;i&gt;Method:&lt;\/i&gt; 57 women, aged 18.1\u201341.5 years, were treated with estrogen from puberty induction. &lt;i&gt;Results:&lt;\/i&gt; In 21 women (37%), the uterus developed to &gt;65 mm in length. The daily estrogen dose correlated with both uterine length (r = 0.29; p &lt; 0.05) and Tanner breast stage (r = 0.44; p &lt; 0.001). A negative correlation between age at artificial menarche and uterine length was found (r = \u20130.29; p &lt; 0.05). The endometrium thickness was greater in women with an uterus length &gt;65 mm (p &lt; 0.05). In 50% of the women (18 were evaluated), an adult-shaped uterus developed. Previous growth hormone therapy (n = 32) had no impact on the uterus length. &lt;i&gt;Conclusions:&lt;\/i&gt; The uterine development was suboptimal in most patients. Further investigation is needed to optimize estrogen therapy for uterine development in patients with Turner syndrome.<\/jats:p>","DOI":"10.1159\/000073233","type":"journal-article","created":{"date-parts":[[2003,10,13]],"date-time":"2003-10-13T12:59:58Z","timestamp":1066049998000},"page":"198-204","source":"Crossref","is-referenced-by-count":22,"title":["The Uterine Length in Women with Turner Syndrome Reflects the Postmenarcheal Daily Estrogen Dose"],"prefix":"10.1159","volume":"60","author":[{"given":"Marta","family":"Snajderova","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tonko","family":"Mardesic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Lebl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hedvika","family":"Gerzova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leos","family":"Teslik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jirina","family":"Zapletalova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2003,10,15]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.82.6.1810"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.101.3.486"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1210\/jc.84.12.4510"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1210\/jc.86.5.1936"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1210\/jc.80.11.3384"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2265.2001.01181.x"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1159\/000053246"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1055\/s-2000-12561"}],"container-title":["Hormone Research in Paediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/73233","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/73233","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T03:48:20Z","timestamp":1745466500000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000073233"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003]]},"references-count":8,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2003,7,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000073233","archive":["Portico"],"relation":{},"ISSN":["1663-2818","1663-2826"],"issn-type":[{"value":"1663-2818","type":"print"},{"value":"1663-2826","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003]]}}}