{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T13:11:18Z","timestamp":1760188278612,"version":"3.40.4"},"reference-count":8,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2003,1,1]],"date-time":"2003-01-01T00:00:00Z","timestamp":1041379200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2003,1,1]],"date-time":"2003-01-01T00:00:00Z","timestamp":1041379200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Urol Int"],"published-print":{"date-parts":[[2003]]},"abstract":"<jats:p>&lt;i&gt;Background and Purpose:&lt;\/i&gt; Radiotherapy remains the treatment of choice for patients with stage I seminoma. The aim of this study is to report preliminary results of reduced dose radiotherapy to ipsilateral pelvic and para-aortic lymph nodes. &lt;i&gt;Materials and Methods:&lt;\/i&gt; Between February 1996 and December 2001, 53 patients with stage I testicular seminoma were treated with adjuvant radiotherapy after orchiectomy. The median age was 34 years (19\u201359 years). Four (7.5%) patients had a history of cryptorchidism. Eleven (20.8%) patients showed elevated \u03b2-human chorionic gonadotropin. All patients had a radical inguinal orchiectomy and histopathological analysis yielded classic seminoma in 47 (88.7%), spermatocytic in 5 (9.4%) and anaplastic in 1 (1.9%) patients. A total of 19.6\u201320 Gy in 1.8- to 2-Gy daily fractions was administered to the para-aortic and ipsilateral iliac lymphatics. &lt;i&gt;Results:&lt;\/i&gt; Median follow-up time was 42 months (12\u201377 months). One patient developed para-aortic lymph node recurrence at month 28 of the follow-up. Five-year overall and disease-free survivals were 100 and 98%, respectively. Only grade I\u2013II of the Radiation Therapy Oncology Group acute gastrointestinal complications without any severe late toxicity was detected. &lt;i&gt;Conclusion:&lt;\/i&gt; Reduced dose radiotherapy seems to be as effective as higher doses in the management of stage I seminoma with an acceptable toxicity.<\/jats:p>","DOI":"10.1159\/000074091","type":"journal-article","created":{"date-parts":[[2003,12,19]],"date-time":"2003-12-19T09:25:47Z","timestamp":1071825947000},"page":"385-388","source":"Crossref","is-referenced-by-count":11,"title":["Stage I Testicular Seminoma: Para-Aortic and Iliac Irradiation with Reduced Dose after Orchiectomy"],"prefix":"10.1159","volume":"71","author":[{"given":"Murat","family":"G\u00fcrkaynak","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fadil","family":"Akyol","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Faruk","family":"Zorlu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serap","family":"Akyurek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ferah","family":"Yildiz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u0130. Lale","family":"Atahan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2003,11,28]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/0167-8140(95)01631-P"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(95)00069-B"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(97)00733-5"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(96)00093-4"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/S1078-1439(00)00129-0"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(99)00376-3"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9098(199801)67:1<38::AID-JSO8>3.0.CO;2-N"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(97)00229-0"}],"container-title":["Urologia Internationalis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/74091","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/74091","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T03:49:19Z","timestamp":1745466559000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000074091"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003]]},"references-count":8,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2003,11,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000074091","archive":["Portico"],"relation":{},"ISSN":["0042-1138","1423-0399"],"issn-type":[{"type":"print","value":"0042-1138"},{"type":"electronic","value":"1423-0399"}],"subject":[],"published":{"date-parts":[[2003]]}}}